RAB27B-WDR7 Fusion FISH Probe
The RAB27B-WDR7 Fusion FISH Probe is used to confirm a fusion of the RAB27B and WDR7 genes. The fusion of the RAB27B and WDR7 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RAB27B-WDR7-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RAB27B-WDR7-20-RERE | 20 (40 μL) | 200 μL |
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| RAB27B-WDR7-20-REOR | 20 (40 μL) | 200 μL |
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| RAB27B-WDR7-20-REGO | 20 (40 μL) | 200 μL |
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| RAB27B-WDR7-20-REGR | 20 (40 μL) | 200 μL |
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| RAB27B-WDR7-20-REAQ | 20 (40 μL) | 200 μL |
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| RAB27B-WDR7-20-ORRE | 20 (40 μL) | 200 μL |
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| RAB27B-WDR7-20-OROR | 20 (40 μL) | 200 μL |
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| RAB27B-WDR7-20-ORGO | 20 (40 μL) | 200 μL |
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| RAB27B-WDR7-20-ORAQ | 20 (40 μL) | 200 μL |
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| RAB27B-WDR7-20-GORE | 20 (40 μL) | 200 μL |
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| RAB27B-WDR7-20-GOOR | 20 (40 μL) | 200 μL |
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| RAB27B-WDR7-20-GOGO | 20 (40 μL) | 200 μL |
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| RAB27B-WDR7-20-GOGR | 20 (40 μL) | 200 μL |
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| RAB27B-WDR7-20-GOAQ | 20 (40 μL) | 200 μL |
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| RAB27B-WDR7-20-GRRE | 20 (40 μL) | 200 μL |
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| RAB27B-WDR7-20-GROR | 20 (40 μL) | 200 μL |
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| RAB27B-WDR7-20-GRGO | 20 (40 μL) | 200 μL |
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| RAB27B-WDR7-20-GRGR | 20 (40 μL) | 200 μL |
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| RAB27B-WDR7-20-GRAQ | 20 (40 μL) | 200 μL |
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| RAB27B-WDR7-20-AQRE | 20 (40 μL) | 200 μL |
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| RAB27B-WDR7-20-AQOR | 20 (40 μL) | 200 μL |
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| RAB27B-WDR7-20-AQGO | 20 (40 μL) | 200 μL |
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| RAB27B-WDR7-20-AQGR | 20 (40 μL) | 200 μL |
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| RAB27B-WDR7-20-AQAQ | 20 (40 μL) | 200 μL |
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RAB27B Gene Summary
Members of the Rab protein family, including RAB27B, are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking (Chen et al., 1997 [PubMed 9066979]).[supplied by OMIM, Nov 2010]
Gene Name: RAB27B, Member RAS Oncogene Family
Chromosome: CHR18: 52495707 -52562747
Locus: 18q21.2
WDR7 Gene Summary
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) that may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. The encoded protein forms the beta subunit of rabconnectin-3 and binds directly with Rab3A GDP/GTP exchange protein and indirectly with Rab3A GDP/GTP activating protein; these proteins are regulators of Rab3 small G protein family members involved in control of the calcium-dependant exocytosis of neurotransmitters. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Name: WD Repeat Domain 7
Chromosome: CHR18: 54318615 -54697036
Locus: 18q21.31
Gene Diseases
The RAB27B WDR7 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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