RAB28-STAP1 Fusion FISH Probe
The RAB28-STAP1 Fusion FISH Probe is used to confirm a fusion of the RAB28 and STAP1 genes. The fusion of the RAB28 and STAP1 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RAB28-STAP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RAB28-STAP1-20-RERE | 20 (40 μL) | 200 μL |
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| RAB28-STAP1-20-REOR | 20 (40 μL) | 200 μL |
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| RAB28-STAP1-20-REGO | 20 (40 μL) | 200 μL |
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| RAB28-STAP1-20-REGR | 20 (40 μL) | 200 μL |
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| RAB28-STAP1-20-REAQ | 20 (40 μL) | 200 μL |
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| RAB28-STAP1-20-ORRE | 20 (40 μL) | 200 μL |
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| RAB28-STAP1-20-OROR | 20 (40 μL) | 200 μL |
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| RAB28-STAP1-20-ORGO | 20 (40 μL) | 200 μL |
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| RAB28-STAP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| RAB28-STAP1-20-GORE | 20 (40 μL) | 200 μL |
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| RAB28-STAP1-20-GOOR | 20 (40 μL) | 200 μL |
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| RAB28-STAP1-20-GOGO | 20 (40 μL) | 200 μL |
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| RAB28-STAP1-20-GOGR | 20 (40 μL) | 200 μL |
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| RAB28-STAP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| RAB28-STAP1-20-GRRE | 20 (40 μL) | 200 μL |
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| RAB28-STAP1-20-GROR | 20 (40 μL) | 200 μL |
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| RAB28-STAP1-20-GRGO | 20 (40 μL) | 200 μL |
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| RAB28-STAP1-20-GRGR | 20 (40 μL) | 200 μL |
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| RAB28-STAP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| RAB28-STAP1-20-AQRE | 20 (40 μL) | 200 μL |
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| RAB28-STAP1-20-AQOR | 20 (40 μL) | 200 μL |
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| RAB28-STAP1-20-AQGO | 20 (40 μL) | 200 μL |
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| RAB28-STAP1-20-AQGR | 20 (40 μL) | 200 μL |
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| RAB28-STAP1-20-AQAQ | 20 (40 μL) | 200 μL |
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RAB28 Gene Summary
This gene encodes a member of the Rab subfamily of Ras-related small GTPases. The encoded protein may be involved in regulating intracellular trafficking. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 9 and X. [provided by RefSeq, Apr 2009]
Gene Name: RAB28, Member RAS Oncogene Family
Chromosome: CHR4: 13369346 -13485989
Locus: 4p15.33
STAP1 Gene Summary
The protein encoded by this gene contains a proline-rich region, a pleckstrin homology (PH) domain, and a region in the carboxy terminal half with similarity to the Src Homology 2 (SH2) domain. This protein is a substrate of tyrosine-protein kinase Tec, and its interaction with tyrosine-protein kinase Tec is phosphorylation-dependent. This protein is thought to participate in a positive feedback loop by upregulating the activity of tyrosine-protein kinase Tec. Variants of this gene have been associated with autosomal-dominant hypercholesterolemia (ADH), which is characterized by elevated low-density lipoprotein cholesterol levels and in increased risk of coronary vascular disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Gene Name: Signal Transducing Adaptor Family Member 1
Chromosome: CHR4: 68424445 -68472616
Locus: 4q13.2
Gene Diseases
The RAB28 STAP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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