RAB3GAP1-CCNT2 Fusion FISH Probe
The RAB3GAP1-CCNT2 Fusion FISH Probe is used to confirm a fusion of the RAB3GAP1 and CCNT2 genes. The fusion of the RAB3GAP1 and CCNT2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RAB3GAP1-CCNT2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RAB3GAP1-CCNT2-20-RERE | 20 (40 μL) | 200 μL |
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| RAB3GAP1-CCNT2-20-REOR | 20 (40 μL) | 200 μL |
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| RAB3GAP1-CCNT2-20-REGO | 20 (40 μL) | 200 μL |
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| RAB3GAP1-CCNT2-20-REGR | 20 (40 μL) | 200 μL |
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| RAB3GAP1-CCNT2-20-REAQ | 20 (40 μL) | 200 μL |
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| RAB3GAP1-CCNT2-20-ORRE | 20 (40 μL) | 200 μL |
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| RAB3GAP1-CCNT2-20-OROR | 20 (40 μL) | 200 μL |
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| RAB3GAP1-CCNT2-20-ORGO | 20 (40 μL) | 200 μL |
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| RAB3GAP1-CCNT2-20-ORAQ | 20 (40 μL) | 200 μL |
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| RAB3GAP1-CCNT2-20-GORE | 20 (40 μL) | 200 μL |
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| RAB3GAP1-CCNT2-20-GOOR | 20 (40 μL) | 200 μL |
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| RAB3GAP1-CCNT2-20-GOGO | 20 (40 μL) | 200 μL |
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| RAB3GAP1-CCNT2-20-GOGR | 20 (40 μL) | 200 μL |
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| RAB3GAP1-CCNT2-20-GOAQ | 20 (40 μL) | 200 μL |
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| RAB3GAP1-CCNT2-20-GRRE | 20 (40 μL) | 200 μL |
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| RAB3GAP1-CCNT2-20-GROR | 20 (40 μL) | 200 μL |
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| RAB3GAP1-CCNT2-20-GRGO | 20 (40 μL) | 200 μL |
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| RAB3GAP1-CCNT2-20-GRGR | 20 (40 μL) | 200 μL |
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| RAB3GAP1-CCNT2-20-GRAQ | 20 (40 μL) | 200 μL |
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| RAB3GAP1-CCNT2-20-AQRE | 20 (40 μL) | 200 μL |
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| RAB3GAP1-CCNT2-20-AQOR | 20 (40 μL) | 200 μL |
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| RAB3GAP1-CCNT2-20-AQGO | 20 (40 μL) | 200 μL |
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| RAB3GAP1-CCNT2-20-AQGR | 20 (40 μL) | 200 μL |
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| RAB3GAP1-CCNT2-20-AQAQ | 20 (40 μL) | 200 μL |
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CCNT2 Gene Summary
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. A pseudogene of this gene is found on chromosome 1. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010]
Gene Name: Cyclin T2
Chromosome: CHR2: 135676391 -135716915
Locus: 2q21.3
RAB3GAP1 Gene Summary
This gene encodes the catalytic subunit of a Rab GTPase activating protein. The encoded protein forms a heterodimer with a non-catalytic subunit to specifically regulate the activity of members of the Rab3 subfamily of small G proteins. This protein mediates the hydrolysis of GTP bound Rab3 to the GDP bound form. Mutations in this gene are associated with Warburg micro syndrome. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]
Gene Name: RAB3 GTPase Activating Protein Catalytic Subunit 1
Chromosome: CHR2: 135809834 -135928279
Locus: 2q21.3
Gene Diseases
The RAB3GAP1 CCNT2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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