RAB3GAP1-LRP1B Fusion FISH Probe
The RAB3GAP1-LRP1B Fusion FISH Probe is used to confirm a fusion of the RAB3GAP1 and LRP1B genes. The fusion of the RAB3GAP1 and LRP1B genes has been associated with Kidney Renal Papillary Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RAB3GAP1-LRP1B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RAB3GAP1-LRP1B-20-RERE | 20 (40 μL) | 200 μL |
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| RAB3GAP1-LRP1B-20-REOR | 20 (40 μL) | 200 μL |
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| RAB3GAP1-LRP1B-20-REGO | 20 (40 μL) | 200 μL |
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| RAB3GAP1-LRP1B-20-REGR | 20 (40 μL) | 200 μL |
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| RAB3GAP1-LRP1B-20-REAQ | 20 (40 μL) | 200 μL |
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| RAB3GAP1-LRP1B-20-ORRE | 20 (40 μL) | 200 μL |
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| RAB3GAP1-LRP1B-20-OROR | 20 (40 μL) | 200 μL |
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| RAB3GAP1-LRP1B-20-ORGO | 20 (40 μL) | 200 μL |
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| RAB3GAP1-LRP1B-20-ORAQ | 20 (40 μL) | 200 μL |
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| RAB3GAP1-LRP1B-20-GORE | 20 (40 μL) | 200 μL |
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| RAB3GAP1-LRP1B-20-GOOR | 20 (40 μL) | 200 μL |
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| RAB3GAP1-LRP1B-20-GOGO | 20 (40 μL) | 200 μL |
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| RAB3GAP1-LRP1B-20-GOGR | 20 (40 μL) | 200 μL |
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| RAB3GAP1-LRP1B-20-GOAQ | 20 (40 μL) | 200 μL |
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| RAB3GAP1-LRP1B-20-GRRE | 20 (40 μL) | 200 μL |
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| RAB3GAP1-LRP1B-20-GROR | 20 (40 μL) | 200 μL |
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| RAB3GAP1-LRP1B-20-GRGO | 20 (40 μL) | 200 μL |
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| RAB3GAP1-LRP1B-20-GRGR | 20 (40 μL) | 200 μL |
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| RAB3GAP1-LRP1B-20-GRAQ | 20 (40 μL) | 200 μL |
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| RAB3GAP1-LRP1B-20-AQRE | 20 (40 μL) | 200 μL |
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| RAB3GAP1-LRP1B-20-AQOR | 20 (40 μL) | 200 μL |
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| RAB3GAP1-LRP1B-20-AQGO | 20 (40 μL) | 200 μL |
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| RAB3GAP1-LRP1B-20-AQGR | 20 (40 μL) | 200 μL |
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| RAB3GAP1-LRP1B-20-AQAQ | 20 (40 μL) | 200 μL |
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RAB3GAP1 Gene Summary
This gene encodes the catalytic subunit of a Rab GTPase activating protein. The encoded protein forms a heterodimer with a non-catalytic subunit to specifically regulate the activity of members of the Rab3 subfamily of small G proteins. This protein mediates the hydrolysis of GTP bound Rab3 to the GDP bound form. Mutations in this gene are associated with Warburg micro syndrome. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]
Gene Name: RAB3 GTPase Activating Protein Catalytic Subunit 1
Chromosome: CHR2: 135809834 -135928279
Locus: 2q21.3
LRP1B Gene Summary
This gene encodes a member of the low density lipoprotein (LDL) receptor family. These receptors play a wide variety of roles in normal cell function and development due to their interactions with multiple ligands. Disruption of this gene has been reported in several types of cancer. [provided by RefSeq, Jun 2016]
Gene Name: LDL Receptor Related Protein 1B
Chromosome: CHR2: 140988995 -142889270
Locus: 2q22.1-q22.2
Gene Diseases
The RAB3GAP1 LRP1B Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Papillary Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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