RAB4B-FBXL12 Fusion FISH Probe
The RAB4B-FBXL12 Fusion FISH Probe is used to confirm a fusion of the RAB4B and FBXL12 genes. The fusion of the RAB4B and FBXL12 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RAB4B-FBXL12-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RAB4B-FBXL12-20-RERE | 20 (40 μL) | 200 μL |
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| RAB4B-FBXL12-20-REOR | 20 (40 μL) | 200 μL |
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| RAB4B-FBXL12-20-REGO | 20 (40 μL) | 200 μL |
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| RAB4B-FBXL12-20-REGR | 20 (40 μL) | 200 μL |
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| RAB4B-FBXL12-20-REAQ | 20 (40 μL) | 200 μL |
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| RAB4B-FBXL12-20-ORRE | 20 (40 μL) | 200 μL |
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| RAB4B-FBXL12-20-OROR | 20 (40 μL) | 200 μL |
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| RAB4B-FBXL12-20-ORGO | 20 (40 μL) | 200 μL |
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| RAB4B-FBXL12-20-ORAQ | 20 (40 μL) | 200 μL |
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| RAB4B-FBXL12-20-GORE | 20 (40 μL) | 200 μL |
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| RAB4B-FBXL12-20-GOOR | 20 (40 μL) | 200 μL |
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| RAB4B-FBXL12-20-GOGO | 20 (40 μL) | 200 μL |
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| RAB4B-FBXL12-20-GOGR | 20 (40 μL) | 200 μL |
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| RAB4B-FBXL12-20-GOAQ | 20 (40 μL) | 200 μL |
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| RAB4B-FBXL12-20-GRRE | 20 (40 μL) | 200 μL |
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| RAB4B-FBXL12-20-GROR | 20 (40 μL) | 200 μL |
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| RAB4B-FBXL12-20-GRGO | 20 (40 μL) | 200 μL |
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| RAB4B-FBXL12-20-GRGR | 20 (40 μL) | 200 μL |
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| RAB4B-FBXL12-20-GRAQ | 20 (40 μL) | 200 μL |
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| RAB4B-FBXL12-20-AQRE | 20 (40 μL) | 200 μL |
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| RAB4B-FBXL12-20-AQOR | 20 (40 μL) | 200 μL |
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| RAB4B-FBXL12-20-AQGO | 20 (40 μL) | 200 μL |
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| RAB4B-FBXL12-20-AQGR | 20 (40 μL) | 200 μL |
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| RAB4B-FBXL12-20-AQAQ | 20 (40 μL) | 200 μL |
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RAB4B Gene Summary
RAB proteins, such as RAB4B, are members of the RAS superfamily of small GTPases that are involved in vesicular trafficking (He et al., 2002 [PubMed 12450215]).[supplied by OMIM, Aug 2009]
Gene Name: RAB4B, Member RAS Oncogene Family
Chromosome: CHR19: 41284123 -41302849
Locus: 19q13.2
FBXL12 Gene Summary
Members of the F-box protein family, such as FBXL12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Gene Name: F-box And Leucine Rich Repeat Protein 12
Chromosome: CHR19: 9920942 -9929731
Locus: 19p13.2
Gene Diseases
The RAB4B FBXL12 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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