RAB6A-HIST1H2AC Fusion FISH Probe
The RAB6A-HIST1H2AC Fusion FISH Probe is used to confirm a fusion of the RAB6A and HIST1H2AC genes. The fusion of the RAB6A and HIST1H2AC genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RAB6A-HIST1H2AC-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RAB6A-HIST1H2AC-20-RERE | 20 (40 μL) | 200 μL |
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| RAB6A-HIST1H2AC-20-REOR | 20 (40 μL) | 200 μL |
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| RAB6A-HIST1H2AC-20-REGO | 20 (40 μL) | 200 μL |
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| RAB6A-HIST1H2AC-20-REGR | 20 (40 μL) | 200 μL |
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| RAB6A-HIST1H2AC-20-REAQ | 20 (40 μL) | 200 μL |
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| RAB6A-HIST1H2AC-20-ORRE | 20 (40 μL) | 200 μL |
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| RAB6A-HIST1H2AC-20-OROR | 20 (40 μL) | 200 μL |
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| RAB6A-HIST1H2AC-20-ORGO | 20 (40 μL) | 200 μL |
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| RAB6A-HIST1H2AC-20-ORAQ | 20 (40 μL) | 200 μL |
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| RAB6A-HIST1H2AC-20-GORE | 20 (40 μL) | 200 μL |
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| RAB6A-HIST1H2AC-20-GOOR | 20 (40 μL) | 200 μL |
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| RAB6A-HIST1H2AC-20-GOGO | 20 (40 μL) | 200 μL |
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| RAB6A-HIST1H2AC-20-GOGR | 20 (40 μL) | 200 μL |
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| RAB6A-HIST1H2AC-20-GOAQ | 20 (40 μL) | 200 μL |
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| RAB6A-HIST1H2AC-20-GRRE | 20 (40 μL) | 200 μL |
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| RAB6A-HIST1H2AC-20-GROR | 20 (40 μL) | 200 μL |
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| RAB6A-HIST1H2AC-20-GRGO | 20 (40 μL) | 200 μL |
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| RAB6A-HIST1H2AC-20-GRGR | 20 (40 μL) | 200 μL |
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| RAB6A-HIST1H2AC-20-GRAQ | 20 (40 μL) | 200 μL |
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| RAB6A-HIST1H2AC-20-AQRE | 20 (40 μL) | 200 μL |
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| RAB6A-HIST1H2AC-20-AQOR | 20 (40 μL) | 200 μL |
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| RAB6A-HIST1H2AC-20-AQGO | 20 (40 μL) | 200 μL |
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| RAB6A-HIST1H2AC-20-AQGR | 20 (40 μL) | 200 μL |
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| RAB6A-HIST1H2AC-20-AQAQ | 20 (40 μL) | 200 μL |
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RAB6A Gene Summary
This gene encodes a member of the RAB family, which belongs to the small GTPase superfamily. GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments. This protein is located at the Golgi apparatus, which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions. Myosin II is an effector of this protein in these processes. This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1, which interacts with the HCMV virion tegument protein, pp150. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
Gene Name: RAB6A, Member RAS Oncogene Family
Chromosome: CHR11: 73386682 -73472201
Locus: 11q13.4
HIST1H2AC Gene Summary
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015]
Gene Name: Histone Cluster 1 H2A Family Member C
Chromosome: CHR6: 26124372 -26124918
Locus: 6p22.2
Gene Diseases
The RAB6A HIST1H2AC Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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