RAC3-ABCA8 Fusion FISH Probe
The RAC3-ABCA8 Fusion FISH Probe is used to confirm a fusion of the RAC3 and ABCA8 genes. The fusion of the RAC3 and ABCA8 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RAC3-ABCA8-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RAC3-ABCA8-20-RERE | 20 (40 μL) | 200 μL |
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| RAC3-ABCA8-20-REOR | 20 (40 μL) | 200 μL |
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| RAC3-ABCA8-20-REGO | 20 (40 μL) | 200 μL |
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| RAC3-ABCA8-20-REGR | 20 (40 μL) | 200 μL |
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| RAC3-ABCA8-20-REAQ | 20 (40 μL) | 200 μL |
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| RAC3-ABCA8-20-ORRE | 20 (40 μL) | 200 μL |
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| RAC3-ABCA8-20-OROR | 20 (40 μL) | 200 μL |
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| RAC3-ABCA8-20-ORGO | 20 (40 μL) | 200 μL |
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| RAC3-ABCA8-20-ORAQ | 20 (40 μL) | 200 μL |
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| RAC3-ABCA8-20-GORE | 20 (40 μL) | 200 μL |
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| RAC3-ABCA8-20-GOOR | 20 (40 μL) | 200 μL |
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| RAC3-ABCA8-20-GOGO | 20 (40 μL) | 200 μL |
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| RAC3-ABCA8-20-GOGR | 20 (40 μL) | 200 μL |
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| RAC3-ABCA8-20-GOAQ | 20 (40 μL) | 200 μL |
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| RAC3-ABCA8-20-GRRE | 20 (40 μL) | 200 μL |
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| RAC3-ABCA8-20-GROR | 20 (40 μL) | 200 μL |
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| RAC3-ABCA8-20-GRGO | 20 (40 μL) | 200 μL |
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| RAC3-ABCA8-20-GRGR | 20 (40 μL) | 200 μL |
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| RAC3-ABCA8-20-GRAQ | 20 (40 μL) | 200 μL |
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| RAC3-ABCA8-20-AQRE | 20 (40 μL) | 200 μL |
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| RAC3-ABCA8-20-AQOR | 20 (40 μL) | 200 μL |
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| RAC3-ABCA8-20-AQGO | 20 (40 μL) | 200 μL |
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| RAC3-ABCA8-20-AQGR | 20 (40 μL) | 200 μL |
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| RAC3-ABCA8-20-AQAQ | 20 (40 μL) | 200 μL |
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RAC3 Gene Summary
The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Gene Name: Rac Family Small GTPase 3
Chromosome: CHR17: 79989531 -79992080
Locus: 17q25.3
ABCA8 Gene Summary
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The encoded protein may regulate lipid metabolism and be involved in the formation and maintenance of myelin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Gene Name: ATP Binding Cassette Subfamily A Member 8
Chromosome: CHR17: 66863430 -66951533
Locus: 17q24.2
Gene Diseases
The RAC3 ABCA8 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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