RAD1-SPEF2 Fusion FISH Probe
The RAD1-SPEF2 Fusion FISH Probe is used to confirm a fusion of the RAD1 and SPEF2 genes. The fusion of the RAD1 and SPEF2 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RAD1-SPEF2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RAD1-SPEF2-20-RERE | 20 (40 μL) | 200 μL |
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| RAD1-SPEF2-20-REOR | 20 (40 μL) | 200 μL |
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| RAD1-SPEF2-20-REGO | 20 (40 μL) | 200 μL |
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| RAD1-SPEF2-20-REGR | 20 (40 μL) | 200 μL |
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| RAD1-SPEF2-20-REAQ | 20 (40 μL) | 200 μL |
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| RAD1-SPEF2-20-ORRE | 20 (40 μL) | 200 μL |
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| RAD1-SPEF2-20-OROR | 20 (40 μL) | 200 μL |
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| RAD1-SPEF2-20-ORGO | 20 (40 μL) | 200 μL |
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| RAD1-SPEF2-20-ORAQ | 20 (40 μL) | 200 μL |
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| RAD1-SPEF2-20-GORE | 20 (40 μL) | 200 μL |
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| RAD1-SPEF2-20-GOOR | 20 (40 μL) | 200 μL |
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| RAD1-SPEF2-20-GOGO | 20 (40 μL) | 200 μL |
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| RAD1-SPEF2-20-GOGR | 20 (40 μL) | 200 μL |
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| RAD1-SPEF2-20-GOAQ | 20 (40 μL) | 200 μL |
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| RAD1-SPEF2-20-GRRE | 20 (40 μL) | 200 μL |
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| RAD1-SPEF2-20-GROR | 20 (40 μL) | 200 μL |
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| RAD1-SPEF2-20-GRGO | 20 (40 μL) | 200 μL |
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| RAD1-SPEF2-20-GRGR | 20 (40 μL) | 200 μL |
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| RAD1-SPEF2-20-GRAQ | 20 (40 μL) | 200 μL |
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| RAD1-SPEF2-20-AQRE | 20 (40 μL) | 200 μL |
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| RAD1-SPEF2-20-AQOR | 20 (40 μL) | 200 μL |
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| RAD1-SPEF2-20-AQGO | 20 (40 μL) | 200 μL |
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| RAD1-SPEF2-20-AQGR | 20 (40 μL) | 200 μL |
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| RAD1-SPEF2-20-AQAQ | 20 (40 μL) | 200 μL |
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RAD1 Gene Summary
This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Jan 2009]
Gene Name: RAD1 Checkpoint DNA Exonuclease
Chromosome: CHR5: 34905365 -34915780
Locus: 5p13.2
SPEF2 Gene Summary
The Sperm Flagellar 2 (SPEF2) gene is located on chr5 :35617988-35814713 at 5p13.2.
Gene Name: Sperm Flagellar 2
Chromosome: CHR5: 35617988 -35814713
Locus: 5p13.2
Gene Diseases
The RAD1 SPEF2 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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