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RAMP1-RBM44 Fusion FISH Probe

The RAMP1-RBM44 Fusion FISH Probe is used to confirm a fusion of the RAMP1 and RBM44 genes. The fusion of the RAMP1 and RBM44 genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
RAMP1-RBM44-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
RAMP1-RBM44-20-RERE 20 (40 μL) 200 μL
RAMP1-RBM44-20-REOR 20 (40 μL) 200 μL
RAMP1-RBM44-20-REGO 20 (40 μL) 200 μL
RAMP1-RBM44-20-REGR 20 (40 μL) 200 μL
RAMP1-RBM44-20-REAQ 20 (40 μL) 200 μL
RAMP1-RBM44-20-ORRE 20 (40 μL) 200 μL
RAMP1-RBM44-20-OROR 20 (40 μL) 200 μL
RAMP1-RBM44-20-ORGO 20 (40 μL) 200 μL
RAMP1-RBM44-20-ORAQ 20 (40 μL) 200 μL
RAMP1-RBM44-20-GORE 20 (40 μL) 200 μL
RAMP1-RBM44-20-GOOR 20 (40 μL) 200 μL
RAMP1-RBM44-20-GOGO 20 (40 μL) 200 μL
RAMP1-RBM44-20-GOGR 20 (40 μL) 200 μL
RAMP1-RBM44-20-GOAQ 20 (40 μL) 200 μL
RAMP1-RBM44-20-GRRE 20 (40 μL) 200 μL
RAMP1-RBM44-20-GROR 20 (40 μL) 200 μL
RAMP1-RBM44-20-GRGO 20 (40 μL) 200 μL
RAMP1-RBM44-20-GRGR 20 (40 μL) 200 μL
RAMP1-RBM44-20-GRAQ 20 (40 μL) 200 μL
RAMP1-RBM44-20-AQRE 20 (40 μL) 200 μL
RAMP1-RBM44-20-AQOR 20 (40 μL) 200 μL
RAMP1-RBM44-20-AQGO 20 (40 μL) 200 μL
RAMP1-RBM44-20-AQGR 20 (40 μL) 200 μL
RAMP1-RBM44-20-AQAQ 20 (40 μL) 200 μL

RAMP1 Gene Summary

The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]

Gene Name: Receptor Activity Modifying Protein 1

Chromosome: CHR2: 238768186 -238820755

Locus: 2q37.3

RBM44 Gene Summary

The RNA Binding Motif Protein 44 (RBM44) gene is located on chr2 :238707387-238751451 at 2q37.3.

Gene Name: RNA Binding Motif Protein 44

Chromosome: CHR2: 238707387 -238751451

Locus: 2q37.3

Gene Diseases

The RAMP1 RBM44 Fusion has been associated with the following diseases:

Disease Name
Colon Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.