RAP1B-CPM Fusion FISH Probe
The RAP1B-CPM Fusion FISH Probe is used to confirm a fusion of the RAP1B and CPM genes. The fusion of the RAP1B and CPM genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RAP1B-CPM-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| RAP1B-CPM-20-RERE | 20 (40 μL) | 200 μL |
|
|
| RAP1B-CPM-20-REOR | 20 (40 μL) | 200 μL |
|
|
| RAP1B-CPM-20-REGO | 20 (40 μL) | 200 μL |
|
|
| RAP1B-CPM-20-REGR | 20 (40 μL) | 200 μL |
|
|
| RAP1B-CPM-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| RAP1B-CPM-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| RAP1B-CPM-20-OROR | 20 (40 μL) | 200 μL |
|
|
| RAP1B-CPM-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| RAP1B-CPM-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| RAP1B-CPM-20-GORE | 20 (40 μL) | 200 μL |
|
|
| RAP1B-CPM-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| RAP1B-CPM-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| RAP1B-CPM-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| RAP1B-CPM-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| RAP1B-CPM-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| RAP1B-CPM-20-GROR | 20 (40 μL) | 200 μL |
|
|
| RAP1B-CPM-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| RAP1B-CPM-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| RAP1B-CPM-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| RAP1B-CPM-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| RAP1B-CPM-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| RAP1B-CPM-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| RAP1B-CPM-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| RAP1B-CPM-20-AQAQ | 20 (40 μL) | 200 μL |
|
CPM Gene Summary
The protein encoded by this gene is a membrane-bound arginine/lysine carboxypeptidase. Its expression is associated with monocyte to macrophage differentiation. This encoded protein contains hydrophobic regions at the amino and carboxy termini and has 6 potential asparagine-linked glycosylation sites. The active site residues of carboxypeptidases A and B are conserved in this protein. Three alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Carboxypeptidase M
Chromosome: CHR12: 69244955 -69357020
Locus: 12q15
RAP1B Gene Summary
This gene encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This protein also plays a role in regulating outside-in signaling in platelets. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 5, 6 and 9. [provided by RefSeq, Oct 2011]
Gene Name: RAP1B, Member Of RAS Oncogene Family
Chromosome: CHR12: 69004651 -69054374
Locus: 12q15
Gene Diseases
The RAP1B CPM Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Glioblastoma Multiforme |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|