SEARCH OUR PRODUCT CATALOG

RAP1GAP-GOLGB1 Fusion FISH Probe

The RAP1GAP-GOLGB1 Fusion FISH Probe is used to confirm a fusion of the RAP1GAP and GOLGB1 genes. The fusion of the RAP1GAP and GOLGB1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
RAP1GAP-GOLGB1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
RAP1GAP-GOLGB1-20-RERE 20 (40 μL) 200 μL
RAP1GAP-GOLGB1-20-REOR 20 (40 μL) 200 μL
RAP1GAP-GOLGB1-20-REGO 20 (40 μL) 200 μL
RAP1GAP-GOLGB1-20-REGR 20 (40 μL) 200 μL
RAP1GAP-GOLGB1-20-REAQ 20 (40 μL) 200 μL
RAP1GAP-GOLGB1-20-ORRE 20 (40 μL) 200 μL
RAP1GAP-GOLGB1-20-OROR 20 (40 μL) 200 μL
RAP1GAP-GOLGB1-20-ORGO 20 (40 μL) 200 μL
RAP1GAP-GOLGB1-20-ORAQ 20 (40 μL) 200 μL
RAP1GAP-GOLGB1-20-GORE 20 (40 μL) 200 μL
RAP1GAP-GOLGB1-20-GOOR 20 (40 μL) 200 μL
RAP1GAP-GOLGB1-20-GOGO 20 (40 μL) 200 μL
RAP1GAP-GOLGB1-20-GOGR 20 (40 μL) 200 μL
RAP1GAP-GOLGB1-20-GOAQ 20 (40 μL) 200 μL
RAP1GAP-GOLGB1-20-GRRE 20 (40 μL) 200 μL
RAP1GAP-GOLGB1-20-GROR 20 (40 μL) 200 μL
RAP1GAP-GOLGB1-20-GRGO 20 (40 μL) 200 μL
RAP1GAP-GOLGB1-20-GRGR 20 (40 μL) 200 μL
RAP1GAP-GOLGB1-20-GRAQ 20 (40 μL) 200 μL
RAP1GAP-GOLGB1-20-AQRE 20 (40 μL) 200 μL
RAP1GAP-GOLGB1-20-AQOR 20 (40 μL) 200 μL
RAP1GAP-GOLGB1-20-AQGO 20 (40 μL) 200 μL
RAP1GAP-GOLGB1-20-AQGR 20 (40 μL) 200 μL
RAP1GAP-GOLGB1-20-AQAQ 20 (40 μL) 200 μL

GOLGB1 Gene Summary

The Golgin B1 (GOLGB1) gene is located on chr3 :121382047-121468602 at 3q13.33.

Gene Name: Golgin B1

Chromosome: CHR3: 121382047 -121468602

Locus: 3q13.33

RAP1GAP Gene Summary

This gene encodes a type of GTPase-activating-protein (GAP) that down-regulates the activity of the ras-related RAP1 protein. RAP1 acts as a molecular switch by cycling between an inactive GDP-bound form and an active GTP-bound form. The product of this gene, RAP1GAP, promotes the hydrolysis of bound GTP and hence returns RAP1 to the inactive state whereas other proteins, guanine nucleotide exchange factors (GEFs), act as RAP1 activators by facilitating the conversion of RAP1 from the GDP- to the GTP-bound form. In general, ras subfamily proteins, such as RAP1, play key roles in receptor-linked signaling pathways that control cell growth and differentiation. RAP1 plays a role in diverse processes such as cell proliferation, adhesion, differentiation, and embryogenesis. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Aug 2011]

Gene Name: RAP1 GTPase Activating Protein

Chromosome: CHR1: 21922707 -21995856

Locus: 1p36.12

Gene Diseases

The RAP1GAP GOLGB1 Fusion has been associated with the following diseases:

Disease Name
Prostate Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.