RAPGEF1-WDR83 Fusion FISH Probe
The RAPGEF1-WDR83 Fusion FISH Probe is used to confirm a fusion of the RAPGEF1 and WDR83 genes. The fusion of the RAPGEF1 and WDR83 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RAPGEF1-WDR83-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RAPGEF1-WDR83-20-RERE | 20 (40 μL) | 200 μL |
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| RAPGEF1-WDR83-20-REOR | 20 (40 μL) | 200 μL |
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| RAPGEF1-WDR83-20-REGO | 20 (40 μL) | 200 μL |
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| RAPGEF1-WDR83-20-REGR | 20 (40 μL) | 200 μL |
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| RAPGEF1-WDR83-20-REAQ | 20 (40 μL) | 200 μL |
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| RAPGEF1-WDR83-20-ORRE | 20 (40 μL) | 200 μL |
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| RAPGEF1-WDR83-20-OROR | 20 (40 μL) | 200 μL |
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| RAPGEF1-WDR83-20-ORGO | 20 (40 μL) | 200 μL |
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| RAPGEF1-WDR83-20-ORAQ | 20 (40 μL) | 200 μL |
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| RAPGEF1-WDR83-20-GORE | 20 (40 μL) | 200 μL |
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| RAPGEF1-WDR83-20-GOOR | 20 (40 μL) | 200 μL |
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| RAPGEF1-WDR83-20-GOGO | 20 (40 μL) | 200 μL |
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| RAPGEF1-WDR83-20-GOGR | 20 (40 μL) | 200 μL |
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| RAPGEF1-WDR83-20-GOAQ | 20 (40 μL) | 200 μL |
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| RAPGEF1-WDR83-20-GRRE | 20 (40 μL) | 200 μL |
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| RAPGEF1-WDR83-20-GROR | 20 (40 μL) | 200 μL |
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| RAPGEF1-WDR83-20-GRGO | 20 (40 μL) | 200 μL |
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| RAPGEF1-WDR83-20-GRGR | 20 (40 μL) | 200 μL |
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| RAPGEF1-WDR83-20-GRAQ | 20 (40 μL) | 200 μL |
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| RAPGEF1-WDR83-20-AQRE | 20 (40 μL) | 200 μL |
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| RAPGEF1-WDR83-20-AQOR | 20 (40 μL) | 200 μL |
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| RAPGEF1-WDR83-20-AQGO | 20 (40 μL) | 200 μL |
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| RAPGEF1-WDR83-20-AQGR | 20 (40 μL) | 200 μL |
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| RAPGEF1-WDR83-20-AQAQ | 20 (40 μL) | 200 μL |
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RAPGEF1 Gene Summary
This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: Rap Guanine Nucleotide Exchange Factor 1
Chromosome: CHR9: 134452156 -134612925
Locus: 9q34.13
WDR83 Gene Summary
This gene encodes a member of the WD-40 protein family. The protein is proposed to function as a molecular scaffold for various multimeric protein complexes. The protein associates with several components of the extracellular signal-regulated kinase (ERK) pathway, and promotes ERK activity in response to serum or other signals. The protein also interacts with egl nine homolog 3 (EGLN3, also known as PHD3) and regulates expression of hypoxia-inducible factor 1, and has been purified as part of the spliceosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Gene Name: WD Repeat Domain 83
Chromosome: CHR19: 12777617 -12786646
Locus: 19p13.13
Gene Diseases
The RAPGEF1 WDR83 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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