RARA-CA10 Fusion FISH Probe
The RARA-CA10 Fusion FISH Probe is used to confirm a fusion of the RARA and CA10 genes. The fusion of the RARA and CA10 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RARA-CA10-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RARA-CA10-20-RERE | 20 (40 μL) | 200 μL |
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| RARA-CA10-20-REOR | 20 (40 μL) | 200 μL |
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| RARA-CA10-20-REGO | 20 (40 μL) | 200 μL |
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| RARA-CA10-20-REGR | 20 (40 μL) | 200 μL |
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| RARA-CA10-20-REAQ | 20 (40 μL) | 200 μL |
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| RARA-CA10-20-ORRE | 20 (40 μL) | 200 μL |
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| RARA-CA10-20-OROR | 20 (40 μL) | 200 μL |
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| RARA-CA10-20-ORGO | 20 (40 μL) | 200 μL |
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| RARA-CA10-20-ORAQ | 20 (40 μL) | 200 μL |
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| RARA-CA10-20-GORE | 20 (40 μL) | 200 μL |
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| RARA-CA10-20-GOOR | 20 (40 μL) | 200 μL |
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| RARA-CA10-20-GOGO | 20 (40 μL) | 200 μL |
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| RARA-CA10-20-GOGR | 20 (40 μL) | 200 μL |
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| RARA-CA10-20-GOAQ | 20 (40 μL) | 200 μL |
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| RARA-CA10-20-GRRE | 20 (40 μL) | 200 μL |
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| RARA-CA10-20-GROR | 20 (40 μL) | 200 μL |
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| RARA-CA10-20-GRGO | 20 (40 μL) | 200 μL |
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| RARA-CA10-20-GRGR | 20 (40 μL) | 200 μL |
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| RARA-CA10-20-GRAQ | 20 (40 μL) | 200 μL |
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| RARA-CA10-20-AQRE | 20 (40 μL) | 200 μL |
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| RARA-CA10-20-AQOR | 20 (40 μL) | 200 μL |
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| RARA-CA10-20-AQGO | 20 (40 μL) | 200 μL |
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| RARA-CA10-20-AQGR | 20 (40 μL) | 200 μL |
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| RARA-CA10-20-AQAQ | 20 (40 μL) | 200 μL |
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RARA Gene Summary
This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.[provided by RefSeq, Sep 2010]
Gene Name: Retinoic Acid Receptor Alpha
Chromosome: CHR17: 38465422 -38513895
Locus: 17q21.2
CA10 Gene Summary
This gene encodes a protein that belongs to the carbonic anhydrase family of zinc metalloenzymes, which catalyze the reversible hydration of carbon dioxide in various biological processes. The protein encoded by this gene is an acatalytic member of the alpha-carbonic anhydrase subgroup, and it is thought to play a role in the central nervous system, especially in brain development. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Carbonic Anhydrase 10
Chromosome: CHR17: 49707673 -50237377
Locus: 17q21.33-q22
Gene Diseases
The RARA CA10 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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