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RARA-CDK12 Fusion FISH Probe

The RARA-CDK12 Fusion FISH Probe is used to confirm a fusion of the RARA and CDK12 genes. The fusion of the RARA and CDK12 genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
RARA-CDK12-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
RARA-CDK12-20-RERE 20 (40 μL) 200 μL
RARA-CDK12-20-REOR 20 (40 μL) 200 μL
RARA-CDK12-20-REGO 20 (40 μL) 200 μL
RARA-CDK12-20-REGR 20 (40 μL) 200 μL
RARA-CDK12-20-REAQ 20 (40 μL) 200 μL
RARA-CDK12-20-ORRE 20 (40 μL) 200 μL
RARA-CDK12-20-OROR 20 (40 μL) 200 μL
RARA-CDK12-20-ORGO 20 (40 μL) 200 μL
RARA-CDK12-20-ORAQ 20 (40 μL) 200 μL
RARA-CDK12-20-GORE 20 (40 μL) 200 μL
RARA-CDK12-20-GOOR 20 (40 μL) 200 μL
RARA-CDK12-20-GOGO 20 (40 μL) 200 μL
RARA-CDK12-20-GOGR 20 (40 μL) 200 μL
RARA-CDK12-20-GOAQ 20 (40 μL) 200 μL
RARA-CDK12-20-GRRE 20 (40 μL) 200 μL
RARA-CDK12-20-GROR 20 (40 μL) 200 μL
RARA-CDK12-20-GRGO 20 (40 μL) 200 μL
RARA-CDK12-20-GRGR 20 (40 μL) 200 μL
RARA-CDK12-20-GRAQ 20 (40 μL) 200 μL
RARA-CDK12-20-AQRE 20 (40 μL) 200 μL
RARA-CDK12-20-AQOR 20 (40 μL) 200 μL
RARA-CDK12-20-AQGO 20 (40 μL) 200 μL
RARA-CDK12-20-AQGR 20 (40 μL) 200 μL
RARA-CDK12-20-AQAQ 20 (40 μL) 200 μL

RARA Gene Summary

This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.[provided by RefSeq, Sep 2010]

Gene Name: Retinoic Acid Receptor Alpha

Chromosome: CHR17: 38465422 -38513895

Locus: 17q21.2

CDK12 Gene Summary

The Cyclin Dependent Kinase 12 (CDK12) gene is located on chr17 :37617738-37690800 at 17q12.

Gene Name: Cyclin Dependent Kinase 12

Chromosome: CHR17: 37617738 -37690800

Locus: 17q12

Gene Diseases

The RARA CDK12 Fusion has been associated with the following diseases:

Disease Name
Ovarian Serous Cystadenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.