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RASGRP1-CD47 Fusion FISH Probe

The RASGRP1-CD47 Fusion FISH Probe is used to confirm a fusion of the RASGRP1 and CD47 genes. The fusion of the RASGRP1 and CD47 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
RASGRP1-CD47-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
RASGRP1-CD47-20-RERE 20 (40 μL) 200 μL
RASGRP1-CD47-20-REOR 20 (40 μL) 200 μL
RASGRP1-CD47-20-REGO 20 (40 μL) 200 μL
RASGRP1-CD47-20-REGR 20 (40 μL) 200 μL
RASGRP1-CD47-20-REAQ 20 (40 μL) 200 μL
RASGRP1-CD47-20-ORRE 20 (40 μL) 200 μL
RASGRP1-CD47-20-OROR 20 (40 μL) 200 μL
RASGRP1-CD47-20-ORGO 20 (40 μL) 200 μL
RASGRP1-CD47-20-ORAQ 20 (40 μL) 200 μL
RASGRP1-CD47-20-GORE 20 (40 μL) 200 μL
RASGRP1-CD47-20-GOOR 20 (40 μL) 200 μL
RASGRP1-CD47-20-GOGO 20 (40 μL) 200 μL
RASGRP1-CD47-20-GOGR 20 (40 μL) 200 μL
RASGRP1-CD47-20-GOAQ 20 (40 μL) 200 μL
RASGRP1-CD47-20-GRRE 20 (40 μL) 200 μL
RASGRP1-CD47-20-GROR 20 (40 μL) 200 μL
RASGRP1-CD47-20-GRGO 20 (40 μL) 200 μL
RASGRP1-CD47-20-GRGR 20 (40 μL) 200 μL
RASGRP1-CD47-20-GRAQ 20 (40 μL) 200 μL
RASGRP1-CD47-20-AQRE 20 (40 μL) 200 μL
RASGRP1-CD47-20-AQOR 20 (40 μL) 200 μL
RASGRP1-CD47-20-AQGO 20 (40 μL) 200 μL
RASGRP1-CD47-20-AQGR 20 (40 μL) 200 μL
RASGRP1-CD47-20-AQAQ 20 (40 μL) 200 μL

CD47 Gene Summary

This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2010]

Gene Name: CD47 Molecule

Chromosome: CHR3: 107761940 -107809935

Locus: 3q13.12

RASGRP1 Gene Summary

This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE). [provided by RefSeq, Jul 2008]

Gene Name: RAS Guanyl Releasing Protein 1

Chromosome: CHR15: 38780301 -38857007

Locus: 15q14

Gene Diseases

The RASGRP1 CD47 Fusion has been associated with the following diseases:

Disease Name
Uterine Corpus Endometrial Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.