RASSF3-STK10 Fusion FISH Probe
The RASSF3-STK10 Fusion FISH Probe is used to confirm a fusion of the RASSF3 and STK10 genes. The fusion of the RASSF3 and STK10 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RASSF3-STK10-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RASSF3-STK10-20-RERE | 20 (40 μL) | 200 μL |
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| RASSF3-STK10-20-REOR | 20 (40 μL) | 200 μL |
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| RASSF3-STK10-20-REGO | 20 (40 μL) | 200 μL |
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| RASSF3-STK10-20-REGR | 20 (40 μL) | 200 μL |
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| RASSF3-STK10-20-REAQ | 20 (40 μL) | 200 μL |
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| RASSF3-STK10-20-ORRE | 20 (40 μL) | 200 μL |
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| RASSF3-STK10-20-OROR | 20 (40 μL) | 200 μL |
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| RASSF3-STK10-20-ORGO | 20 (40 μL) | 200 μL |
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| RASSF3-STK10-20-ORAQ | 20 (40 μL) | 200 μL |
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| RASSF3-STK10-20-GORE | 20 (40 μL) | 200 μL |
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| RASSF3-STK10-20-GOOR | 20 (40 μL) | 200 μL |
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| RASSF3-STK10-20-GOGO | 20 (40 μL) | 200 μL |
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| RASSF3-STK10-20-GOGR | 20 (40 μL) | 200 μL |
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| RASSF3-STK10-20-GOAQ | 20 (40 μL) | 200 μL |
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| RASSF3-STK10-20-GRRE | 20 (40 μL) | 200 μL |
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| RASSF3-STK10-20-GROR | 20 (40 μL) | 200 μL |
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| RASSF3-STK10-20-GRGO | 20 (40 μL) | 200 μL |
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| RASSF3-STK10-20-GRGR | 20 (40 μL) | 200 μL |
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| RASSF3-STK10-20-GRAQ | 20 (40 μL) | 200 μL |
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| RASSF3-STK10-20-AQRE | 20 (40 μL) | 200 μL |
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| RASSF3-STK10-20-AQOR | 20 (40 μL) | 200 μL |
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| RASSF3-STK10-20-AQGO | 20 (40 μL) | 200 μL |
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| RASSF3-STK10-20-AQGR | 20 (40 μL) | 200 μL |
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| RASSF3-STK10-20-AQAQ | 20 (40 μL) | 200 μL |
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STK10 Gene Summary
This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway. [provided by RefSeq, Jul 2008]
Gene Name: Serine/threonine Kinase 10
Chromosome: CHR5: 171469073 -171615346
Locus: 5q35.1
RASSF3 Gene Summary
The RAS oncogene (MIM 190020) is mutated in nearly one-third of all human cancers. Members of the RAS superfamily are plasma membrane GTP-binding proteins that modulate intracellular signal transduction pathways. A subfamily of RAS effectors, including RASSF3, share a RAS association (RA) domain.[supplied by OMIM, Jul 2003]
Gene Name: Ras Association Domain Family Member 3
Chromosome: CHR12: 65004292 -65091347
Locus: 12q14.2
Gene Diseases
The RASSF3 STK10 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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