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RASSF5-IKBKE Fusion FISH Probe

The RASSF5-IKBKE Fusion FISH Probe is used to confirm a fusion of the RASSF5 and IKBKE genes. The fusion of the RASSF5 and IKBKE genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
RASSF5-IKBKE-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
RASSF5-IKBKE-20-RERE 20 (40 μL) 200 μL
RASSF5-IKBKE-20-REOR 20 (40 μL) 200 μL
RASSF5-IKBKE-20-REGO 20 (40 μL) 200 μL
RASSF5-IKBKE-20-REGR 20 (40 μL) 200 μL
RASSF5-IKBKE-20-REAQ 20 (40 μL) 200 μL
RASSF5-IKBKE-20-ORRE 20 (40 μL) 200 μL
RASSF5-IKBKE-20-OROR 20 (40 μL) 200 μL
RASSF5-IKBKE-20-ORGO 20 (40 μL) 200 μL
RASSF5-IKBKE-20-ORAQ 20 (40 μL) 200 μL
RASSF5-IKBKE-20-GORE 20 (40 μL) 200 μL
RASSF5-IKBKE-20-GOOR 20 (40 μL) 200 μL
RASSF5-IKBKE-20-GOGO 20 (40 μL) 200 μL
RASSF5-IKBKE-20-GOGR 20 (40 μL) 200 μL
RASSF5-IKBKE-20-GOAQ 20 (40 μL) 200 μL
RASSF5-IKBKE-20-GRRE 20 (40 μL) 200 μL
RASSF5-IKBKE-20-GROR 20 (40 μL) 200 μL
RASSF5-IKBKE-20-GRGO 20 (40 μL) 200 μL
RASSF5-IKBKE-20-GRGR 20 (40 μL) 200 μL
RASSF5-IKBKE-20-GRAQ 20 (40 μL) 200 μL
RASSF5-IKBKE-20-AQRE 20 (40 μL) 200 μL
RASSF5-IKBKE-20-AQOR 20 (40 μL) 200 μL
RASSF5-IKBKE-20-AQGO 20 (40 μL) 200 μL
RASSF5-IKBKE-20-AQGR 20 (40 μL) 200 μL
RASSF5-IKBKE-20-AQAQ 20 (40 μL) 200 μL

IKBKE Gene Summary

IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).[supplied by OMIM, Oct 2009]

Gene Name: Inhibitor Of Nuclear Factor Kappa B Kinase Subunit Epsilon

Chromosome: CHR1: 206643585 -206670223

Locus: 1q32.1

RASSF5 Gene Summary

This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules, and associates with the GTP-activated forms of Ras, Rap1, and several other Ras-like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Name: Ras Association Domain Family Member 5

Chromosome: CHR1: 206680878 -206762616

Locus: 1q32.1

Gene Diseases

The RASSF5 IKBKE Fusion has been associated with the following diseases:

Disease Name
Head And Neck Squamous Cell Carcinoma 

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.