RB1CC1-SNX16 Fusion FISH Probe
The RB1CC1-SNX16 Fusion FISH Probe is used to confirm a fusion of the RB1CC1 and SNX16 genes. The fusion of the RB1CC1 and SNX16 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RB1CC1-SNX16-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RB1CC1-SNX16-20-RERE | 20 (40 μL) | 200 μL |
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| RB1CC1-SNX16-20-REOR | 20 (40 μL) | 200 μL |
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| RB1CC1-SNX16-20-REGO | 20 (40 μL) | 200 μL |
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| RB1CC1-SNX16-20-REGR | 20 (40 μL) | 200 μL |
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| RB1CC1-SNX16-20-REAQ | 20 (40 μL) | 200 μL |
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| RB1CC1-SNX16-20-ORRE | 20 (40 μL) | 200 μL |
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| RB1CC1-SNX16-20-OROR | 20 (40 μL) | 200 μL |
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| RB1CC1-SNX16-20-ORGO | 20 (40 μL) | 200 μL |
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| RB1CC1-SNX16-20-ORAQ | 20 (40 μL) | 200 μL |
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| RB1CC1-SNX16-20-GORE | 20 (40 μL) | 200 μL |
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| RB1CC1-SNX16-20-GOOR | 20 (40 μL) | 200 μL |
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| RB1CC1-SNX16-20-GOGO | 20 (40 μL) | 200 μL |
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| RB1CC1-SNX16-20-GOGR | 20 (40 μL) | 200 μL |
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| RB1CC1-SNX16-20-GOAQ | 20 (40 μL) | 200 μL |
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| RB1CC1-SNX16-20-GRRE | 20 (40 μL) | 200 μL |
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| RB1CC1-SNX16-20-GROR | 20 (40 μL) | 200 μL |
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| RB1CC1-SNX16-20-GRGO | 20 (40 μL) | 200 μL |
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| RB1CC1-SNX16-20-GRGR | 20 (40 μL) | 200 μL |
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| RB1CC1-SNX16-20-GRAQ | 20 (40 μL) | 200 μL |
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| RB1CC1-SNX16-20-AQRE | 20 (40 μL) | 200 μL |
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| RB1CC1-SNX16-20-AQOR | 20 (40 μL) | 200 μL |
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| RB1CC1-SNX16-20-AQGO | 20 (40 μL) | 200 μL |
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| RB1CC1-SNX16-20-AQGR | 20 (40 μL) | 200 μL |
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| RB1CC1-SNX16-20-AQAQ | 20 (40 μL) | 200 μL |
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RB1CC1 Gene Summary
The protein encoded by this gene interacts with signaling pathways to coordinately regulate cell growth, cell proliferation, apoptosis, autophagy, and cell migration. This tumor suppressor also enhances retinoblastoma 1 gene expression in cancer cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2009]
Gene Name: RB1 Inducible Coiled-coil 1
Chromosome: CHR8: 53535017 -53627026
Locus: 8q11.23
SNX16 Gene Summary
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. The protein encoded by this gene associates with late endosome membranes as is involved in tubule formation, cholesterol transport, and transport of tetraspanin CD81. The encoded protein also inhibits cell migration and tumorigenesis. [provided by RefSeq, Jan 2017]
Gene Name: Sorting Nexin 16
Chromosome: CHR8: 82711817 -82754521
Locus: 8q21.13
Gene Diseases
The RB1CC1 SNX16 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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