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RBBP8-FAM126A Fusion FISH Probe

The RBBP8-FAM126A Fusion FISH Probe is used to confirm a fusion of the RBBP8 and FAM126A genes. The fusion of the RBBP8 and FAM126A genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
RBBP8-FAM126A-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
RBBP8-FAM126A-20-RERE 20 (40 μL) 200 μL
RBBP8-FAM126A-20-REOR 20 (40 μL) 200 μL
RBBP8-FAM126A-20-REGO 20 (40 μL) 200 μL
RBBP8-FAM126A-20-REGR 20 (40 μL) 200 μL
RBBP8-FAM126A-20-REAQ 20 (40 μL) 200 μL
RBBP8-FAM126A-20-ORRE 20 (40 μL) 200 μL
RBBP8-FAM126A-20-OROR 20 (40 μL) 200 μL
RBBP8-FAM126A-20-ORGO 20 (40 μL) 200 μL
RBBP8-FAM126A-20-ORAQ 20 (40 μL) 200 μL
RBBP8-FAM126A-20-GORE 20 (40 μL) 200 μL
RBBP8-FAM126A-20-GOOR 20 (40 μL) 200 μL
RBBP8-FAM126A-20-GOGO 20 (40 μL) 200 μL
RBBP8-FAM126A-20-GOGR 20 (40 μL) 200 μL
RBBP8-FAM126A-20-GOAQ 20 (40 μL) 200 μL
RBBP8-FAM126A-20-GRRE 20 (40 μL) 200 μL
RBBP8-FAM126A-20-GROR 20 (40 μL) 200 μL
RBBP8-FAM126A-20-GRGO 20 (40 μL) 200 μL
RBBP8-FAM126A-20-GRGR 20 (40 μL) 200 μL
RBBP8-FAM126A-20-GRAQ 20 (40 μL) 200 μL
RBBP8-FAM126A-20-AQRE 20 (40 μL) 200 μL
RBBP8-FAM126A-20-AQOR 20 (40 μL) 200 μL
RBBP8-FAM126A-20-AQGO 20 (40 μL) 200 μL
RBBP8-FAM126A-20-AQGR 20 (40 μL) 200 μL
RBBP8-FAM126A-20-AQAQ 20 (40 μL) 200 μL

RBBP8 Gene Summary

The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined. [provided by RefSeq, Jul 2008]

Gene Name: RB Binding Protein 8, Endonuclease

Chromosome: CHR18: 20513294 -20606449

Locus: 18q11.2

FAM126A Gene Summary

The protein encoded by this gene may play a part in the beta-catenin/Lef signaling pathway. Expression of this gene is down-regulated by beta-catenin. Defects in this gene are a cause of hypomyelination with congenital cataract (HCC). [provided by RefSeq, Oct 2008]

Gene Name: Family With Sequence Similarity 126 Member A

Chromosome: CHR7: 22980877 -23053770

Locus: 7p15.3

Gene Diseases

The RBBP8 FAM126A Fusion has been associated with the following diseases:

Disease Name
Brain Lower Grade Glioma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.