RBM12B-RSPO2 Fusion FISH Probe
The RBM12B-RSPO2 Fusion FISH Probe is used to confirm a fusion of the RBM12B and RSPO2 genes. The fusion of the RBM12B and RSPO2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RBM12B-RSPO2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RBM12B-RSPO2-20-RERE | 20 (40 μL) | 200 μL |
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| RBM12B-RSPO2-20-REOR | 20 (40 μL) | 200 μL |
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| RBM12B-RSPO2-20-REGO | 20 (40 μL) | 200 μL |
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| RBM12B-RSPO2-20-REGR | 20 (40 μL) | 200 μL |
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| RBM12B-RSPO2-20-REAQ | 20 (40 μL) | 200 μL |
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| RBM12B-RSPO2-20-ORRE | 20 (40 μL) | 200 μL |
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| RBM12B-RSPO2-20-OROR | 20 (40 μL) | 200 μL |
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| RBM12B-RSPO2-20-ORGO | 20 (40 μL) | 200 μL |
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| RBM12B-RSPO2-20-ORAQ | 20 (40 μL) | 200 μL |
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| RBM12B-RSPO2-20-GORE | 20 (40 μL) | 200 μL |
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| RBM12B-RSPO2-20-GOOR | 20 (40 μL) | 200 μL |
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| RBM12B-RSPO2-20-GOGO | 20 (40 μL) | 200 μL |
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| RBM12B-RSPO2-20-GOGR | 20 (40 μL) | 200 μL |
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| RBM12B-RSPO2-20-GOAQ | 20 (40 μL) | 200 μL |
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| RBM12B-RSPO2-20-GRRE | 20 (40 μL) | 200 μL |
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| RBM12B-RSPO2-20-GROR | 20 (40 μL) | 200 μL |
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| RBM12B-RSPO2-20-GRGO | 20 (40 μL) | 200 μL |
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| RBM12B-RSPO2-20-GRGR | 20 (40 μL) | 200 μL |
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| RBM12B-RSPO2-20-GRAQ | 20 (40 μL) | 200 μL |
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| RBM12B-RSPO2-20-AQRE | 20 (40 μL) | 200 μL |
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| RBM12B-RSPO2-20-AQOR | 20 (40 μL) | 200 μL |
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| RBM12B-RSPO2-20-AQGO | 20 (40 μL) | 200 μL |
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| RBM12B-RSPO2-20-AQGR | 20 (40 μL) | 200 μL |
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| RBM12B-RSPO2-20-AQAQ | 20 (40 μL) | 200 μL |
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RSPO2 Gene Summary
This gene encodes a member of the R-spondin family of proteins. These proteins are secreted ligands of leucine-rich repeat containing G protein-coupled receptors that enhance Wnt signaling through the inhibition of ubiquitin E3 ligases. A chromosomal translocation including this locus that results in the formation of a gene fusion has been identified in multiple human cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Gene Name: R-spondin 2
Chromosome: CHR8: 108911543 -109095913
Locus: 8q23.1
RBM12B Gene Summary
The RNA Binding Motif Protein 12B (RBM12B) gene is located on chr8 :94743730-94753224 at 8q22.1.
Gene Name: RNA Binding Motif Protein 12B
Chromosome: CHR8: 94743730 -94753224
Locus: 8q22.1
Gene Diseases
The RBM12B RSPO2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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