RBM14-BBS1 Fusion FISH Probe
The RBM14-BBS1 Fusion FISH Probe is used to confirm a fusion of the RBM14 and BBS1 genes. The fusion of the RBM14 and BBS1 genes has been associated with Adrenocortical Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RBM14-BBS1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RBM14-BBS1-20-RERE | 20 (40 μL) | 200 μL |
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| RBM14-BBS1-20-REOR | 20 (40 μL) | 200 μL |
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| RBM14-BBS1-20-REGO | 20 (40 μL) | 200 μL |
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| RBM14-BBS1-20-REGR | 20 (40 μL) | 200 μL |
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| RBM14-BBS1-20-REAQ | 20 (40 μL) | 200 μL |
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| RBM14-BBS1-20-ORRE | 20 (40 μL) | 200 μL |
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| RBM14-BBS1-20-OROR | 20 (40 μL) | 200 μL |
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| RBM14-BBS1-20-ORGO | 20 (40 μL) | 200 μL |
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| RBM14-BBS1-20-ORAQ | 20 (40 μL) | 200 μL |
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| RBM14-BBS1-20-GORE | 20 (40 μL) | 200 μL |
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| RBM14-BBS1-20-GOOR | 20 (40 μL) | 200 μL |
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| RBM14-BBS1-20-GOGO | 20 (40 μL) | 200 μL |
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| RBM14-BBS1-20-GOGR | 20 (40 μL) | 200 μL |
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| RBM14-BBS1-20-GOAQ | 20 (40 μL) | 200 μL |
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| RBM14-BBS1-20-GRRE | 20 (40 μL) | 200 μL |
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| RBM14-BBS1-20-GROR | 20 (40 μL) | 200 μL |
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| RBM14-BBS1-20-GRGO | 20 (40 μL) | 200 μL |
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| RBM14-BBS1-20-GRGR | 20 (40 μL) | 200 μL |
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| RBM14-BBS1-20-GRAQ | 20 (40 μL) | 200 μL |
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| RBM14-BBS1-20-AQRE | 20 (40 μL) | 200 μL |
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| RBM14-BBS1-20-AQOR | 20 (40 μL) | 200 μL |
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| RBM14-BBS1-20-AQGO | 20 (40 μL) | 200 μL |
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| RBM14-BBS1-20-AQGR | 20 (40 μL) | 200 μL |
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| RBM14-BBS1-20-AQAQ | 20 (40 μL) | 200 μL |
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BBS1 Gene Summary
Mutations in this gene have been observed in patients with the major form (type 1) of Bardet-Biedl syndrome. The encoded protein may play a role in eye, limb, cardiac and reproductive system development. [provided by RefSeq, Jul 2008]
Gene Name: Bardet-Biedl Syndrome 1
Chromosome: CHR11: 66278118 -66301084
Locus: 11q13.2
RBM14 Gene Summary
This gene encodes a ribonucleoprotein that functions as a general nuclear coactivator, and an RNA splicing modulator. This protein contains two RNA recognition motifs (RRM) at the N-terminus, and multiple hexapeptide repeat domain at the C-terminus that interacts with thyroid hormone receptor-binding protein (TRBP), and is required for transcription activation. Alternatively spliced transcript variants encoding different isoforms (with opposing effects on transcription) have been described for this gene. [provided by RefSeq, Oct 2011]
Gene Name: RNA Binding Motif Protein 14
Chromosome: CHR11: 66384052 -66397397
Locus: 11q13.2
Gene Diseases
The RBM14 BBS1 Fusion has been associated with the following diseases:
| Disease Name |
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| Adrenocortical Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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