RBM27-LARS Fusion FISH Probe
The RBM27-LARS Fusion FISH Probe is used to confirm a fusion of the RBM27 and LARS genes. The fusion of the RBM27 and LARS genes has been associated with Lymphoid Neoplasm Diffuse Large B-cell Lymphoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RBM27-LARS-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RBM27-LARS-20-RERE | 20 (40 μL) | 200 μL |
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| RBM27-LARS-20-REOR | 20 (40 μL) | 200 μL |
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| RBM27-LARS-20-REGO | 20 (40 μL) | 200 μL |
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| RBM27-LARS-20-REGR | 20 (40 μL) | 200 μL |
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| RBM27-LARS-20-REAQ | 20 (40 μL) | 200 μL |
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| RBM27-LARS-20-ORRE | 20 (40 μL) | 200 μL |
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| RBM27-LARS-20-OROR | 20 (40 μL) | 200 μL |
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| RBM27-LARS-20-ORGO | 20 (40 μL) | 200 μL |
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| RBM27-LARS-20-ORAQ | 20 (40 μL) | 200 μL |
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| RBM27-LARS-20-GORE | 20 (40 μL) | 200 μL |
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| RBM27-LARS-20-GOOR | 20 (40 μL) | 200 μL |
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| RBM27-LARS-20-GOGO | 20 (40 μL) | 200 μL |
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| RBM27-LARS-20-GOGR | 20 (40 μL) | 200 μL |
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| RBM27-LARS-20-GOAQ | 20 (40 μL) | 200 μL |
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| RBM27-LARS-20-GRRE | 20 (40 μL) | 200 μL |
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| RBM27-LARS-20-GROR | 20 (40 μL) | 200 μL |
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| RBM27-LARS-20-GRGO | 20 (40 μL) | 200 μL |
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| RBM27-LARS-20-GRGR | 20 (40 μL) | 200 μL |
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| RBM27-LARS-20-GRAQ | 20 (40 μL) | 200 μL |
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| RBM27-LARS-20-AQRE | 20 (40 μL) | 200 μL |
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| RBM27-LARS-20-AQOR | 20 (40 μL) | 200 μL |
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| RBM27-LARS-20-AQGO | 20 (40 μL) | 200 μL |
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| RBM27-LARS-20-AQGR | 20 (40 μL) | 200 μL |
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| RBM27-LARS-20-AQAQ | 20 (40 μL) | 200 μL |
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LARS Gene Summary
This gene encodes a cytosolic leucine-tRNA synthetase, a member of the class I aminoacyl-tRNA synthetase family. The encoded enzyme catalyzes the ATP-dependent ligation of L-leucine to tRNA(Leu). It is found in the cytoplasm as part of a multisynthetase complex and interacts with the arginine tRNA synthetase through its C-terminal domain. A mutation in this gene was found in affected individuals with infantile liver failure syndrome 1. Alternatively spliced transcript variants of this gene have been observed. [provided by RefSeq, Dec 2015]
Gene Name: Leucyl-tRNA Synthetase
Chromosome: CHR5: 145492588 -145562294
Locus: 5q32
RBM27 Gene Summary
The RNA Binding Motif Protein 27 (RBM27) gene is located on chr5 :145583162-145668784 at 5q32.
Gene Name: RNA Binding Motif Protein 27
Chromosome: CHR5: 145583162 -145668784
Locus: 5q32
Gene Diseases
The RBM27 LARS Fusion has been associated with the following diseases:
| Disease Name |
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| Lymphoid Neoplasm Diffuse Large B-cell Lymphoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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