RBM28-AOAH Fusion FISH Probe
The RBM28-AOAH Fusion FISH Probe is used to confirm a fusion of the RBM28 and AOAH genes. The fusion of the RBM28 and AOAH genes has been associated with Thyroid Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RBM28-AOAH-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| RBM28-AOAH-20-RERE | 20 (40 μL) | 200 μL |
|
|
| RBM28-AOAH-20-REOR | 20 (40 μL) | 200 μL |
|
|
| RBM28-AOAH-20-REGO | 20 (40 μL) | 200 μL |
|
|
| RBM28-AOAH-20-REGR | 20 (40 μL) | 200 μL |
|
|
| RBM28-AOAH-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| RBM28-AOAH-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| RBM28-AOAH-20-OROR | 20 (40 μL) | 200 μL |
|
|
| RBM28-AOAH-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| RBM28-AOAH-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| RBM28-AOAH-20-GORE | 20 (40 μL) | 200 μL |
|
|
| RBM28-AOAH-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| RBM28-AOAH-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| RBM28-AOAH-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| RBM28-AOAH-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| RBM28-AOAH-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| RBM28-AOAH-20-GROR | 20 (40 μL) | 200 μL |
|
|
| RBM28-AOAH-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| RBM28-AOAH-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| RBM28-AOAH-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| RBM28-AOAH-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| RBM28-AOAH-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| RBM28-AOAH-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| RBM28-AOAH-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| RBM28-AOAH-20-AQAQ | 20 (40 μL) | 200 μL |
|
AOAH Gene Summary
This locus encodes both the light and heavy subunits of acyloxyacyl hydrolase. The encoded enzyme catalyzes the hydrolysis of acyloxylacyl-linked fatty acyl chains from bacterial lipopolysaccharides, effectively detoxifying these molecules. The encoded protein may play a role in modulating host inflammatory response to gram-negative bacteria. Alternatively spliced transcript variants have been described.[provided by RefSeq, Apr 2010]
Gene Name: Acyloxyacyl Hydrolase
Chromosome: CHR7: 36552548 -36764154
Locus: 7p14.2
RBM28 Gene Summary
The protein encoded by this gene is a specific nucleolar component of the spliceosomal small nuclear ribonucleoprotein (snRNP)complexes . It specifically associates with U1, U2, U4, U5, and U6 small nuclear RNAs (snRNAs), possibly coordinating their transition through the nucleolus. Mutation in this gene causes alopecia, progressive neurological defects, and endocrinopathy (ANE syndrome), a pleiotropic and clinically heterogeneous disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Gene Name: RNA Binding Motif Protein 28
Chromosome: CHR7: 127950435 -127983962
Locus: 7q32.1
Gene Diseases
The RBM28 AOAH Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Thyroid Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|