RCOR1-TECPR2 Fusion FISH Probe
The RCOR1-TECPR2 Fusion FISH Probe is used to confirm a fusion of the RCOR1 and TECPR2 genes. The fusion of the RCOR1 and TECPR2 genes has been associated with Bladder Urothelial Carcinoma, Head And Neck Squamous Cell Carcinoma , and Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RCOR1-TECPR2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RCOR1-TECPR2-20-RERE | 20 (40 μL) | 200 μL |
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| RCOR1-TECPR2-20-REOR | 20 (40 μL) | 200 μL |
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| RCOR1-TECPR2-20-REGO | 20 (40 μL) | 200 μL |
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| RCOR1-TECPR2-20-REGR | 20 (40 μL) | 200 μL |
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| RCOR1-TECPR2-20-REAQ | 20 (40 μL) | 200 μL |
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| RCOR1-TECPR2-20-ORRE | 20 (40 μL) | 200 μL |
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| RCOR1-TECPR2-20-OROR | 20 (40 μL) | 200 μL |
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| RCOR1-TECPR2-20-ORGO | 20 (40 μL) | 200 μL |
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| RCOR1-TECPR2-20-ORAQ | 20 (40 μL) | 200 μL |
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| RCOR1-TECPR2-20-GORE | 20 (40 μL) | 200 μL |
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| RCOR1-TECPR2-20-GOOR | 20 (40 μL) | 200 μL |
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| RCOR1-TECPR2-20-GOGO | 20 (40 μL) | 200 μL |
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| RCOR1-TECPR2-20-GOGR | 20 (40 μL) | 200 μL |
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| RCOR1-TECPR2-20-GOAQ | 20 (40 μL) | 200 μL |
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| RCOR1-TECPR2-20-GRRE | 20 (40 μL) | 200 μL |
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| RCOR1-TECPR2-20-GROR | 20 (40 μL) | 200 μL |
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| RCOR1-TECPR2-20-GRGO | 20 (40 μL) | 200 μL |
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| RCOR1-TECPR2-20-GRGR | 20 (40 μL) | 200 μL |
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| RCOR1-TECPR2-20-GRAQ | 20 (40 μL) | 200 μL |
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| RCOR1-TECPR2-20-AQRE | 20 (40 μL) | 200 μL |
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| RCOR1-TECPR2-20-AQOR | 20 (40 μL) | 200 μL |
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| RCOR1-TECPR2-20-AQGO | 20 (40 μL) | 200 μL |
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| RCOR1-TECPR2-20-AQGR | 20 (40 μL) | 200 μL |
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| RCOR1-TECPR2-20-AQAQ | 20 (40 μL) | 200 μL |
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TECPR2 Gene Summary
The protein encoded by this gene is a member of the tectonin beta-propeller repeat-containing (TECPR) family, and contains both TECPR and tryptophan-aspartic acid repeat (WD repeat) domains. This gene has been implicated in autophagy, as reduced expression levels of this gene have been associated with impaired autophagy. Recessive mutations in this gene have been associated with a hereditary form of spastic paraparesis (HSP). HSP is characterized by progressive spasticity and paralysis of the legs. There is also some evidence linking mutations in this gene with birdshot chorioretinopathy (BSCR), which results in inflammation of the choroid and retina. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
Gene Name: Tectonin Beta-propeller Repeat Containing 2
Chromosome: CHR14: 102829299 -102968818
Locus: 14q32.31
RCOR1 Gene Summary
This gene encodes a protein that is well-conserved, downregulated at birth, and with a specific role in determining neural cell differentiation. The encoded protein binds to the C-terminal domain of REST (repressor element-1 silencing transcription factor). [provided by RefSeq, Aug 2011]
Gene Name: REST Corepressor 1
Chromosome: CHR14: 103058995 -103196913
Locus: 14q32.31-q32.32
Gene Diseases
The RCOR1 TECPR2 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
| Head And Neck Squamous Cell Carcinoma |
| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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