RECQL5-WBP2 Fusion FISH Probe
The RECQL5-WBP2 Fusion FISH Probe is used to confirm a fusion of the RECQL5 and WBP2 genes. The fusion of the RECQL5 and WBP2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RECQL5-WBP2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RECQL5-WBP2-20-RERE | 20 (40 μL) | 200 μL |
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| RECQL5-WBP2-20-REOR | 20 (40 μL) | 200 μL |
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| RECQL5-WBP2-20-REGO | 20 (40 μL) | 200 μL |
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| RECQL5-WBP2-20-REGR | 20 (40 μL) | 200 μL |
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| RECQL5-WBP2-20-REAQ | 20 (40 μL) | 200 μL |
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| RECQL5-WBP2-20-ORRE | 20 (40 μL) | 200 μL |
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| RECQL5-WBP2-20-OROR | 20 (40 μL) | 200 μL |
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| RECQL5-WBP2-20-ORGO | 20 (40 μL) | 200 μL |
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| RECQL5-WBP2-20-ORAQ | 20 (40 μL) | 200 μL |
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| RECQL5-WBP2-20-GORE | 20 (40 μL) | 200 μL |
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| RECQL5-WBP2-20-GOOR | 20 (40 μL) | 200 μL |
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| RECQL5-WBP2-20-GOGO | 20 (40 μL) | 200 μL |
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| RECQL5-WBP2-20-GOGR | 20 (40 μL) | 200 μL |
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| RECQL5-WBP2-20-GOAQ | 20 (40 μL) | 200 μL |
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| RECQL5-WBP2-20-GRRE | 20 (40 μL) | 200 μL |
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| RECQL5-WBP2-20-GROR | 20 (40 μL) | 200 μL |
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| RECQL5-WBP2-20-GRGO | 20 (40 μL) | 200 μL |
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| RECQL5-WBP2-20-GRGR | 20 (40 μL) | 200 μL |
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| RECQL5-WBP2-20-GRAQ | 20 (40 μL) | 200 μL |
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| RECQL5-WBP2-20-AQRE | 20 (40 μL) | 200 μL |
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| RECQL5-WBP2-20-AQOR | 20 (40 μL) | 200 μL |
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| RECQL5-WBP2-20-AQGO | 20 (40 μL) | 200 μL |
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| RECQL5-WBP2-20-AQGR | 20 (40 μL) | 200 μL |
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| RECQL5-WBP2-20-AQAQ | 20 (40 μL) | 200 μL |
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RECQL5 Gene Summary
The protein encoded by this gene is a helicase that is important for genome stability. The encoded protein also prevents aberrant homologous recombination by displacing RAD51 from ssDNA. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
Gene Name: RecQ Like Helicase 5
Chromosome: CHR17: 73622924 -73663269
Locus: 17q25.1
WBP2 Gene Summary
The globular WW domain is composed of 38 to 40 semiconserved amino acids shared by proteins of diverse functions including structural, regulatory, and signaling proteins. The domain is involved in mediating protein-protein interactions through the binding of polyproline ligands. This gene encodes a WW domain binding protein that is a transcriptional coactivator of estrogen receptor alpha and progesterone receptor. Defects in this gene have been associated with hearing impairment. [provided by RefSeq, Jan 2017]
Gene Name: WW Domain Binding Protein 2
Chromosome: CHR17: 73841779 -73851501
Locus: 17q25.1
Gene Diseases
The RECQL5 WBP2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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