REPS2-TXLNG Fusion FISH Probe
The REPS2-TXLNG Fusion FISH Probe is used to confirm a fusion of the REPS2 and TXLNG genes. The fusion of the REPS2 and TXLNG genes has been associated with Colon Adenocarcinoma, Liver Hepatocellular Carcinoma, Adrenocortical Carcinoma, Prostate Adenocarcinoma, and Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| REPS2-TXLNG-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| REPS2-TXLNG-20-RERE | 20 (40 μL) | 200 μL |
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| REPS2-TXLNG-20-REOR | 20 (40 μL) | 200 μL |
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| REPS2-TXLNG-20-REGO | 20 (40 μL) | 200 μL |
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| REPS2-TXLNG-20-REGR | 20 (40 μL) | 200 μL |
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| REPS2-TXLNG-20-REAQ | 20 (40 μL) | 200 μL |
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| REPS2-TXLNG-20-ORRE | 20 (40 μL) | 200 μL |
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| REPS2-TXLNG-20-OROR | 20 (40 μL) | 200 μL |
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| REPS2-TXLNG-20-ORGO | 20 (40 μL) | 200 μL |
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| REPS2-TXLNG-20-ORAQ | 20 (40 μL) | 200 μL |
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| REPS2-TXLNG-20-GORE | 20 (40 μL) | 200 μL |
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| REPS2-TXLNG-20-GOOR | 20 (40 μL) | 200 μL |
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| REPS2-TXLNG-20-GOGO | 20 (40 μL) | 200 μL |
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| REPS2-TXLNG-20-GOGR | 20 (40 μL) | 200 μL |
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| REPS2-TXLNG-20-GOAQ | 20 (40 μL) | 200 μL |
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| REPS2-TXLNG-20-GRRE | 20 (40 μL) | 200 μL |
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| REPS2-TXLNG-20-GROR | 20 (40 μL) | 200 μL |
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| REPS2-TXLNG-20-GRGO | 20 (40 μL) | 200 μL |
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| REPS2-TXLNG-20-GRGR | 20 (40 μL) | 200 μL |
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| REPS2-TXLNG-20-GRAQ | 20 (40 μL) | 200 μL |
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| REPS2-TXLNG-20-AQRE | 20 (40 μL) | 200 μL |
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| REPS2-TXLNG-20-AQOR | 20 (40 μL) | 200 μL |
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| REPS2-TXLNG-20-AQGO | 20 (40 μL) | 200 μL |
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| REPS2-TXLNG-20-AQGR | 20 (40 μL) | 200 μL |
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| REPS2-TXLNG-20-AQAQ | 20 (40 μL) | 200 μL |
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REPS2 Gene Summary
The product of this gene is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: RALBP1 Associated Eps Domain Containing 2
Chromosome: CHRX: 16964813 -17171403
Locus: Xp22.2
TXLNG Gene Summary
This gene encodes a member of the taxilin family. The encoded protein binds to the C-terminal coiled-coil region of syntaxin family members 1A, 3A and 4A, and may play a role in intracellular vesicle trafficking. This gene is up-regulated by lipopolysaccharide and the gene product may be involved in cell cycle regulation. The related mouse protein was also shown to inhibit activating transcription factor 4-mediated transcription and thus regulate bone mass accrual. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
Gene Name: Taxilin Gamma
Chromosome: CHRX: 16804554 -16862642
Locus: Xp22.2
Gene Diseases
The REPS2 TXLNG Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
| Liver Hepatocellular Carcinoma |
| Adrenocortical Carcinoma |
| Prostate Adenocarcinoma |
| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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