RERE-VAMP3 Fusion FISH Probe
The RERE-VAMP3 Fusion FISH Probe is used to confirm a fusion of the RERE and VAMP3 genes. The fusion of the RERE and VAMP3 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RERE-VAMP3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RERE-VAMP3-20-RERE | 20 (40 μL) | 200 μL |
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| RERE-VAMP3-20-REOR | 20 (40 μL) | 200 μL |
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| RERE-VAMP3-20-REGO | 20 (40 μL) | 200 μL |
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| RERE-VAMP3-20-REGR | 20 (40 μL) | 200 μL |
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| RERE-VAMP3-20-REAQ | 20 (40 μL) | 200 μL |
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| RERE-VAMP3-20-ORRE | 20 (40 μL) | 200 μL |
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| RERE-VAMP3-20-OROR | 20 (40 μL) | 200 μL |
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| RERE-VAMP3-20-ORGO | 20 (40 μL) | 200 μL |
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| RERE-VAMP3-20-ORAQ | 20 (40 μL) | 200 μL |
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| RERE-VAMP3-20-GORE | 20 (40 μL) | 200 μL |
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| RERE-VAMP3-20-GOOR | 20 (40 μL) | 200 μL |
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| RERE-VAMP3-20-GOGO | 20 (40 μL) | 200 μL |
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| RERE-VAMP3-20-GOGR | 20 (40 μL) | 200 μL |
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| RERE-VAMP3-20-GOAQ | 20 (40 μL) | 200 μL |
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| RERE-VAMP3-20-GRRE | 20 (40 μL) | 200 μL |
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| RERE-VAMP3-20-GROR | 20 (40 μL) | 200 μL |
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| RERE-VAMP3-20-GRGO | 20 (40 μL) | 200 μL |
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| RERE-VAMP3-20-GRGR | 20 (40 μL) | 200 μL |
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| RERE-VAMP3-20-GRAQ | 20 (40 μL) | 200 μL |
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| RERE-VAMP3-20-AQRE | 20 (40 μL) | 200 μL |
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| RERE-VAMP3-20-AQOR | 20 (40 μL) | 200 μL |
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| RERE-VAMP3-20-AQGO | 20 (40 μL) | 200 μL |
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| RERE-VAMP3-20-AQGR | 20 (40 μL) | 200 μL |
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| RERE-VAMP3-20-AQAQ | 20 (40 μL) | 200 μL |
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RERE Gene Summary
This gene encodes a member of the atrophin family of arginine-glutamic acid (RE) dipeptide repeat-containing proteins. The encoded protein co-localizes with a transcription factor in the nucleus, and its overexpression triggers apoptosis. A similar protein in mouse associates with histone deacetylase and is thought to function as a transcriptional co-repressor during embryonic development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Arginine-glutamic Acid Dipeptide Repeats
Chromosome: CHR1: 8412463 -8877699
Locus: 1p36.23
VAMP3 Gene Summary
Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation. [provided by RefSeq, Jul 2008]
Gene Name: Vesicle Associated Membrane Protein 3
Chromosome: CHR1: 7831328 -7841492
Locus: 1p36.23
Gene Diseases
The RERE VAMP3 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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