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RNASE10-CD38 Fusion FISH Probe

The RNASE10-CD38 Fusion FISH Probe is used to confirm a fusion of the RNASE10 and CD38 genes. The fusion of the RNASE10 and CD38 genes has been associated with Lung Squamous Cell Carcinoma, Head And Neck Squamous Cell Carcinoma , Head And Neck Squamous Cell Carcinoma , and Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
RNASE10-CD38-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
RNASE10-CD38-20-RERE 20 (40 μL) 200 μL
RNASE10-CD38-20-REOR 20 (40 μL) 200 μL
RNASE10-CD38-20-REGO 20 (40 μL) 200 μL
RNASE10-CD38-20-REGR 20 (40 μL) 200 μL
RNASE10-CD38-20-REAQ 20 (40 μL) 200 μL
RNASE10-CD38-20-ORRE 20 (40 μL) 200 μL
RNASE10-CD38-20-OROR 20 (40 μL) 200 μL
RNASE10-CD38-20-ORGO 20 (40 μL) 200 μL
RNASE10-CD38-20-ORAQ 20 (40 μL) 200 μL
RNASE10-CD38-20-GORE 20 (40 μL) 200 μL
RNASE10-CD38-20-GOOR 20 (40 μL) 200 μL
RNASE10-CD38-20-GOGO 20 (40 μL) 200 μL
RNASE10-CD38-20-GOGR 20 (40 μL) 200 μL
RNASE10-CD38-20-GOAQ 20 (40 μL) 200 μL
RNASE10-CD38-20-GRRE 20 (40 μL) 200 μL
RNASE10-CD38-20-GROR 20 (40 μL) 200 μL
RNASE10-CD38-20-GRGO 20 (40 μL) 200 μL
RNASE10-CD38-20-GRGR 20 (40 μL) 200 μL
RNASE10-CD38-20-GRAQ 20 (40 μL) 200 μL
RNASE10-CD38-20-AQRE 20 (40 μL) 200 μL
RNASE10-CD38-20-AQOR 20 (40 μL) 200 μL
RNASE10-CD38-20-AQGO 20 (40 μL) 200 μL
RNASE10-CD38-20-AQGR 20 (40 μL) 200 μL
RNASE10-CD38-20-AQAQ 20 (40 μL) 200 μL

CD38 Gene Summary

The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

Gene Name: CD38 Molecule

Chromosome: CHR4: 15779930 -15850706

Locus: 4p15.32

RNASE10 Gene Summary

The Ribonuclease A Family Member 10 (inactive) (RNASE10) gene is located on chr14 :20978630-20979281 at 14q11.2.

Gene Name: Ribonuclease A Family Member 10 (inactive)

Chromosome: CHR14: 20978630 -20979281

Locus: 14q11.2

Gene Diseases

The RNASE10 CD38 Fusion has been associated with the following diseases:

Disease Name
Lung Squamous Cell Carcinoma
Head And Neck Squamous Cell Carcinoma 
Head And Neck Squamous Cell Carcinoma 
Head And Neck Squamous Cell Carcinoma 

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.