RNASEH2B-AGXT2 Fusion FISH Probe
The RNASEH2B-AGXT2 Fusion FISH Probe is used to confirm a fusion of the RNASEH2B and AGXT2 genes. The fusion of the RNASEH2B and AGXT2 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RNASEH2B-AGXT2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RNASEH2B-AGXT2-20-RERE | 20 (40 μL) | 200 μL |
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| RNASEH2B-AGXT2-20-REOR | 20 (40 μL) | 200 μL |
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| RNASEH2B-AGXT2-20-REGO | 20 (40 μL) | 200 μL |
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| RNASEH2B-AGXT2-20-REGR | 20 (40 μL) | 200 μL |
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| RNASEH2B-AGXT2-20-REAQ | 20 (40 μL) | 200 μL |
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| RNASEH2B-AGXT2-20-ORRE | 20 (40 μL) | 200 μL |
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| RNASEH2B-AGXT2-20-OROR | 20 (40 μL) | 200 μL |
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| RNASEH2B-AGXT2-20-ORGO | 20 (40 μL) | 200 μL |
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| RNASEH2B-AGXT2-20-ORAQ | 20 (40 μL) | 200 μL |
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| RNASEH2B-AGXT2-20-GORE | 20 (40 μL) | 200 μL |
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| RNASEH2B-AGXT2-20-GOOR | 20 (40 μL) | 200 μL |
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| RNASEH2B-AGXT2-20-GOGO | 20 (40 μL) | 200 μL |
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| RNASEH2B-AGXT2-20-GOGR | 20 (40 μL) | 200 μL |
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| RNASEH2B-AGXT2-20-GOAQ | 20 (40 μL) | 200 μL |
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| RNASEH2B-AGXT2-20-GRRE | 20 (40 μL) | 200 μL |
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| RNASEH2B-AGXT2-20-GROR | 20 (40 μL) | 200 μL |
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| RNASEH2B-AGXT2-20-GRGO | 20 (40 μL) | 200 μL |
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| RNASEH2B-AGXT2-20-GRGR | 20 (40 μL) | 200 μL |
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| RNASEH2B-AGXT2-20-GRAQ | 20 (40 μL) | 200 μL |
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| RNASEH2B-AGXT2-20-AQRE | 20 (40 μL) | 200 μL |
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| RNASEH2B-AGXT2-20-AQOR | 20 (40 μL) | 200 μL |
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| RNASEH2B-AGXT2-20-AQGO | 20 (40 μL) | 200 μL |
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| RNASEH2B-AGXT2-20-AQGR | 20 (40 μL) | 200 μL |
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| RNASEH2B-AGXT2-20-AQAQ | 20 (40 μL) | 200 μL |
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AGXT2 Gene Summary
The protein encoded by this gene is a class III pyridoxal-phosphate-dependent mitochondrial aminotransferase. It catalyzes the conversion of glyoxylate to glycine using L-alanine as the amino donor. It is an important regulator of methylarginines and is involved in the control of blood pressure in kidney. Polymorphisms in this gene affect methylarginine and beta-aminoisobutyrate metabolism, and are associated with carotid atherosclerosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Gene Name: Alanine--glyoxylate Aminotransferase 2
Chromosome: CHR5: 34998205 -35048240
Locus: 5p13.2
RNASEH2B Gene Summary
RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2). [provided by RefSeq, Nov 2008]
Gene Name: Ribonuclease H2 Subunit B
Chromosome: CHR13: 51483813 -51544596
Locus: 13q14.3
Gene Diseases
The RNASEH2B AGXT2 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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