RNF167-PLD2 Fusion FISH Probe
The RNF167-PLD2 Fusion FISH Probe is used to confirm a fusion of the RNF167 and PLD2 genes. The fusion of the RNF167 and PLD2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RNF167-PLD2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RNF167-PLD2-20-RERE | 20 (40 μL) | 200 μL |
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| RNF167-PLD2-20-REOR | 20 (40 μL) | 200 μL |
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| RNF167-PLD2-20-REGO | 20 (40 μL) | 200 μL |
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| RNF167-PLD2-20-REGR | 20 (40 μL) | 200 μL |
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| RNF167-PLD2-20-REAQ | 20 (40 μL) | 200 μL |
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| RNF167-PLD2-20-ORRE | 20 (40 μL) | 200 μL |
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| RNF167-PLD2-20-OROR | 20 (40 μL) | 200 μL |
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| RNF167-PLD2-20-ORGO | 20 (40 μL) | 200 μL |
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| RNF167-PLD2-20-ORAQ | 20 (40 μL) | 200 μL |
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| RNF167-PLD2-20-GORE | 20 (40 μL) | 200 μL |
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| RNF167-PLD2-20-GOOR | 20 (40 μL) | 200 μL |
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| RNF167-PLD2-20-GOGO | 20 (40 μL) | 200 μL |
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| RNF167-PLD2-20-GOGR | 20 (40 μL) | 200 μL |
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| RNF167-PLD2-20-GOAQ | 20 (40 μL) | 200 μL |
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| RNF167-PLD2-20-GRRE | 20 (40 μL) | 200 μL |
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| RNF167-PLD2-20-GROR | 20 (40 μL) | 200 μL |
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| RNF167-PLD2-20-GRGO | 20 (40 μL) | 200 μL |
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| RNF167-PLD2-20-GRGR | 20 (40 μL) | 200 μL |
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| RNF167-PLD2-20-GRAQ | 20 (40 μL) | 200 μL |
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| RNF167-PLD2-20-AQRE | 20 (40 μL) | 200 μL |
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| RNF167-PLD2-20-AQOR | 20 (40 μL) | 200 μL |
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| RNF167-PLD2-20-AQGO | 20 (40 μL) | 200 μL |
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| RNF167-PLD2-20-AQGR | 20 (40 μL) | 200 μL |
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| RNF167-PLD2-20-AQAQ | 20 (40 μL) | 200 μL |
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PLD2 Gene Summary
The protein encoded by this gene catalyzes the hydrolysis of phosphatidylcholine to phosphatidic acid and choline. The activity of the encoded enzyme is enhanced by phosphatidylinositol 4,5-bisphosphate and ADP-ribosylation factor-1. This protein localizes to the peripheral membrane and may be involved in cytoskeletal organization, cell cycle control, transcriptional regulation, and/or regulated secretion. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011]
Gene Name: Phospholipase D2
Chromosome: CHR17: 4710395 -4726727
Locus: 17p13.2
RNF167 Gene Summary
RNF167 is an E3 ubiquitin ligase that interacts with TSSC5 (SLC22A18; MIM 602631) and, together with UBCH6 (UBE2E1; MIM 602916), facilitates TSSC5 polyubiquitylation (Yamada and Gorbsky, 2006 [PubMed 16314844]).[supplied by OMIM, Mar 2008]
Gene Name: Ring Finger Protein 167
Chromosome: CHR17: 4843629 -4848517
Locus: 17p13.2
Gene Diseases
The RNF167 PLD2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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