RNF170-CSMD1 Fusion FISH Probe
The RNF170-CSMD1 Fusion FISH Probe is used to confirm a fusion of the RNF170 and CSMD1 genes. The fusion of the RNF170 and CSMD1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RNF170-CSMD1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RNF170-CSMD1-20-RERE | 20 (40 μL) | 200 μL |
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| RNF170-CSMD1-20-REOR | 20 (40 μL) | 200 μL |
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| RNF170-CSMD1-20-REGO | 20 (40 μL) | 200 μL |
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| RNF170-CSMD1-20-REGR | 20 (40 μL) | 200 μL |
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| RNF170-CSMD1-20-REAQ | 20 (40 μL) | 200 μL |
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| RNF170-CSMD1-20-ORRE | 20 (40 μL) | 200 μL |
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| RNF170-CSMD1-20-OROR | 20 (40 μL) | 200 μL |
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| RNF170-CSMD1-20-ORGO | 20 (40 μL) | 200 μL |
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| RNF170-CSMD1-20-ORAQ | 20 (40 μL) | 200 μL |
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| RNF170-CSMD1-20-GORE | 20 (40 μL) | 200 μL |
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| RNF170-CSMD1-20-GOOR | 20 (40 μL) | 200 μL |
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| RNF170-CSMD1-20-GOGO | 20 (40 μL) | 200 μL |
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| RNF170-CSMD1-20-GOGR | 20 (40 μL) | 200 μL |
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| RNF170-CSMD1-20-GOAQ | 20 (40 μL) | 200 μL |
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| RNF170-CSMD1-20-GRRE | 20 (40 μL) | 200 μL |
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| RNF170-CSMD1-20-GROR | 20 (40 μL) | 200 μL |
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| RNF170-CSMD1-20-GRGO | 20 (40 μL) | 200 μL |
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| RNF170-CSMD1-20-GRGR | 20 (40 μL) | 200 μL |
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| RNF170-CSMD1-20-GRAQ | 20 (40 μL) | 200 μL |
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| RNF170-CSMD1-20-AQRE | 20 (40 μL) | 200 μL |
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| RNF170-CSMD1-20-AQOR | 20 (40 μL) | 200 μL |
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| RNF170-CSMD1-20-AQGO | 20 (40 μL) | 200 μL |
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| RNF170-CSMD1-20-AQGR | 20 (40 μL) | 200 μL |
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| RNF170-CSMD1-20-AQAQ | 20 (40 μL) | 200 μL |
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CSMD1 Gene Summary
The CUB And Sushi Multiple Domains 1 (CSMD1) gene is located on chr8 :2792874-4852328 at 8p23.2.
Gene Name: CUB And Sushi Multiple Domains 1
Chromosome: CHR8: 2792874 -4852328
Locus: 8p23.2
RNF170 Gene Summary
This gene encodes a RING domain-containing protein that resides in the endoplasmic reticulum (ER) membrane. This protein functions as an E3 ubiquitin ligase and mediates ubiquitination and processing of inositol 1,4,5-trisphosphate (IP3) receptors via the ER-associated protein degradation pathway. It is recruited to the activated IP3 receptors by the ERLIN1/ERLIN2 complex to which it is constitutively bound. Mutations in this gene are associated with autosomal dominant sensory ataxia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012]
Gene Name: Ring Finger Protein 170
Chromosome: CHR8: 42704779 -42751866
Locus: 8p11.21
Gene Diseases
The RNF170 CSMD1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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