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RNF41-MSRB3 Fusion FISH Probe

The RNF41-MSRB3 Fusion FISH Probe is used to confirm a fusion of the RNF41 and MSRB3 genes. The fusion of the RNF41 and MSRB3 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
RNF41-MSRB3-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
RNF41-MSRB3-20-RERE 20 (40 μL) 200 μL
RNF41-MSRB3-20-REOR 20 (40 μL) 200 μL
RNF41-MSRB3-20-REGO 20 (40 μL) 200 μL
RNF41-MSRB3-20-REGR 20 (40 μL) 200 μL
RNF41-MSRB3-20-REAQ 20 (40 μL) 200 μL
RNF41-MSRB3-20-ORRE 20 (40 μL) 200 μL
RNF41-MSRB3-20-OROR 20 (40 μL) 200 μL
RNF41-MSRB3-20-ORGO 20 (40 μL) 200 μL
RNF41-MSRB3-20-ORAQ 20 (40 μL) 200 μL
RNF41-MSRB3-20-GORE 20 (40 μL) 200 μL
RNF41-MSRB3-20-GOOR 20 (40 μL) 200 μL
RNF41-MSRB3-20-GOGO 20 (40 μL) 200 μL
RNF41-MSRB3-20-GOGR 20 (40 μL) 200 μL
RNF41-MSRB3-20-GOAQ 20 (40 μL) 200 μL
RNF41-MSRB3-20-GRRE 20 (40 μL) 200 μL
RNF41-MSRB3-20-GROR 20 (40 μL) 200 μL
RNF41-MSRB3-20-GRGO 20 (40 μL) 200 μL
RNF41-MSRB3-20-GRGR 20 (40 μL) 200 μL
RNF41-MSRB3-20-GRAQ 20 (40 μL) 200 μL
RNF41-MSRB3-20-AQRE 20 (40 μL) 200 μL
RNF41-MSRB3-20-AQOR 20 (40 μL) 200 μL
RNF41-MSRB3-20-AQGO 20 (40 μL) 200 μL
RNF41-MSRB3-20-AQGR 20 (40 μL) 200 μL
RNF41-MSRB3-20-AQAQ 20 (40 μL) 200 μL

RNF41 Gene Summary

This gene encodes an E3 ubiquitin ligase. The encoded protein plays a role in type 1 cytokine receptor signaling by controlling the balance between JAK2-associated cytokine receptor degradation and ectodomain shedding. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]

Gene Name: Ring Finger Protein 41

Chromosome: CHR12: 56596287 -56615753

Locus: 12q13.3

MSRB3 Gene Summary

The protein encoded by this gene catalyzes the reduction of methionine sulfoxide to methionine. This enzyme acts as a monomer and requires zinc as a cofactor. Several transcript variants encoding two different isoforms have been found for this gene. One of the isoforms localizes to mitochondria while the other localizes to endoplasmic reticula. [provided by RefSeq, Jul 2010]

Gene Name: Methionine Sulfoxide Reductase B3

Chromosome: CHR12: 65672422 -65860687

Locus: 12q14.3

Gene Diseases

The RNF41 MSRB3 Fusion has been associated with the following diseases:

Disease Name
Bladder Urothelial Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.