RNMTL1-ALOX15B Fusion FISH Probe
The RNMTL1-ALOX15B Fusion FISH Probe is used to confirm a fusion of the RNMTL1 and ALOX15B genes. The fusion of the RNMTL1 and ALOX15B genes has been associated with Cholangiocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RNMTL1-ALOX15B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RNMTL1-ALOX15B-20-RERE | 20 (40 μL) | 200 μL |
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| RNMTL1-ALOX15B-20-REOR | 20 (40 μL) | 200 μL |
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| RNMTL1-ALOX15B-20-REGO | 20 (40 μL) | 200 μL |
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| RNMTL1-ALOX15B-20-REGR | 20 (40 μL) | 200 μL |
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| RNMTL1-ALOX15B-20-REAQ | 20 (40 μL) | 200 μL |
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| RNMTL1-ALOX15B-20-ORRE | 20 (40 μL) | 200 μL |
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| RNMTL1-ALOX15B-20-OROR | 20 (40 μL) | 200 μL |
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| RNMTL1-ALOX15B-20-ORGO | 20 (40 μL) | 200 μL |
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| RNMTL1-ALOX15B-20-ORAQ | 20 (40 μL) | 200 μL |
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| RNMTL1-ALOX15B-20-GORE | 20 (40 μL) | 200 μL |
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| RNMTL1-ALOX15B-20-GOOR | 20 (40 μL) | 200 μL |
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| RNMTL1-ALOX15B-20-GOGO | 20 (40 μL) | 200 μL |
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| RNMTL1-ALOX15B-20-GOGR | 20 (40 μL) | 200 μL |
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| RNMTL1-ALOX15B-20-GOAQ | 20 (40 μL) | 200 μL |
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| RNMTL1-ALOX15B-20-GRRE | 20 (40 μL) | 200 μL |
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| RNMTL1-ALOX15B-20-GROR | 20 (40 μL) | 200 μL |
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| RNMTL1-ALOX15B-20-GRGO | 20 (40 μL) | 200 μL |
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| RNMTL1-ALOX15B-20-GRGR | 20 (40 μL) | 200 μL |
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| RNMTL1-ALOX15B-20-GRAQ | 20 (40 μL) | 200 μL |
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| RNMTL1-ALOX15B-20-AQRE | 20 (40 μL) | 200 μL |
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| RNMTL1-ALOX15B-20-AQOR | 20 (40 μL) | 200 μL |
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| RNMTL1-ALOX15B-20-AQGO | 20 (40 μL) | 200 μL |
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| RNMTL1-ALOX15B-20-AQGR | 20 (40 μL) | 200 μL |
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| RNMTL1-ALOX15B-20-AQAQ | 20 (40 μL) | 200 μL |
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ALOX15B Gene Summary
This gene encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Name: Arachidonate 15-lipoxygenase, Type B
Chromosome: CHR17: 7942357 -7952451
Locus: 17p13.1
Gene Diseases
The RNMTL1 ALOX15B Fusion has been associated with the following diseases:
| Disease Name |
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| Cholangiocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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