ROR2-FAM50B Fusion FISH Probe
The ROR2-FAM50B Fusion FISH Probe is used to confirm a fusion of the ROR2 and FAM50B genes. The fusion of the ROR2 and FAM50B genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ROR2-FAM50B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ROR2-FAM50B-20-RERE | 20 (40 μL) | 200 μL |
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| ROR2-FAM50B-20-REOR | 20 (40 μL) | 200 μL |
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| ROR2-FAM50B-20-REGO | 20 (40 μL) | 200 μL |
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| ROR2-FAM50B-20-REGR | 20 (40 μL) | 200 μL |
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| ROR2-FAM50B-20-REAQ | 20 (40 μL) | 200 μL |
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| ROR2-FAM50B-20-ORRE | 20 (40 μL) | 200 μL |
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| ROR2-FAM50B-20-OROR | 20 (40 μL) | 200 μL |
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| ROR2-FAM50B-20-ORGO | 20 (40 μL) | 200 μL |
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| ROR2-FAM50B-20-ORAQ | 20 (40 μL) | 200 μL |
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| ROR2-FAM50B-20-GORE | 20 (40 μL) | 200 μL |
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| ROR2-FAM50B-20-GOOR | 20 (40 μL) | 200 μL |
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| ROR2-FAM50B-20-GOGO | 20 (40 μL) | 200 μL |
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| ROR2-FAM50B-20-GOGR | 20 (40 μL) | 200 μL |
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| ROR2-FAM50B-20-GOAQ | 20 (40 μL) | 200 μL |
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| ROR2-FAM50B-20-GRRE | 20 (40 μL) | 200 μL |
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| ROR2-FAM50B-20-GROR | 20 (40 μL) | 200 μL |
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| ROR2-FAM50B-20-GRGO | 20 (40 μL) | 200 μL |
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| ROR2-FAM50B-20-GRGR | 20 (40 μL) | 200 μL |
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| ROR2-FAM50B-20-GRAQ | 20 (40 μL) | 200 μL |
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| ROR2-FAM50B-20-AQRE | 20 (40 μL) | 200 μL |
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| ROR2-FAM50B-20-AQOR | 20 (40 μL) | 200 μL |
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| ROR2-FAM50B-20-AQGO | 20 (40 μL) | 200 μL |
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| ROR2-FAM50B-20-AQGR | 20 (40 μL) | 200 μL |
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| ROR2-FAM50B-20-AQAQ | 20 (40 μL) | 200 μL |
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ROR2 Gene Summary
The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance. [provided by RefSeq, Jul 2008]
Gene Name: Receptor Tyrosine Kinase Like Orphan Receptor 2
Chromosome: CHR9: 94484877 -94712444
Locus: 9q22.31
FAM50B Gene Summary
This gene contains an intronless ORF that arose from ancestral retroposition. The encoded protein is related to a plant protein that plays a role in the circadian clock. This gene is adjacent to a differentially methylated region (DMR) and is imprinted and paternally expressed in many tissues. [provided by RefSeq, Nov 2015]
Gene Name: Family With Sequence Similarity 50 Member B
Chromosome: CHR6: 3849631 -3851551
Locus: 6p25.2
Gene Diseases
The ROR2 FAM50B Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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