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RPL18-DDX27 Fusion FISH Probe

The RPL18-DDX27 Fusion FISH Probe is used to confirm a fusion of the RPL18 and DDX27 genes. The fusion of the RPL18 and DDX27 genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
RPL18-DDX27-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
RPL18-DDX27-20-RERE 20 (40 μL) 200 μL
RPL18-DDX27-20-REOR 20 (40 μL) 200 μL
RPL18-DDX27-20-REGO 20 (40 μL) 200 μL
RPL18-DDX27-20-REGR 20 (40 μL) 200 μL
RPL18-DDX27-20-REAQ 20 (40 μL) 200 μL
RPL18-DDX27-20-ORRE 20 (40 μL) 200 μL
RPL18-DDX27-20-OROR 20 (40 μL) 200 μL
RPL18-DDX27-20-ORGO 20 (40 μL) 200 μL
RPL18-DDX27-20-ORAQ 20 (40 μL) 200 μL
RPL18-DDX27-20-GORE 20 (40 μL) 200 μL
RPL18-DDX27-20-GOOR 20 (40 μL) 200 μL
RPL18-DDX27-20-GOGO 20 (40 μL) 200 μL
RPL18-DDX27-20-GOGR 20 (40 μL) 200 μL
RPL18-DDX27-20-GOAQ 20 (40 μL) 200 μL
RPL18-DDX27-20-GRRE 20 (40 μL) 200 μL
RPL18-DDX27-20-GROR 20 (40 μL) 200 μL
RPL18-DDX27-20-GRGO 20 (40 μL) 200 μL
RPL18-DDX27-20-GRGR 20 (40 μL) 200 μL
RPL18-DDX27-20-GRAQ 20 (40 μL) 200 μL
RPL18-DDX27-20-AQRE 20 (40 μL) 200 μL
RPL18-DDX27-20-AQOR 20 (40 μL) 200 μL
RPL18-DDX27-20-AQGO 20 (40 μL) 200 μL
RPL18-DDX27-20-AQGR 20 (40 μL) 200 μL
RPL18-DDX27-20-AQAQ 20 (40 μL) 200 μL

RPL18 Gene Summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L18E family of ribosomal proteins that is a component of the 60S subunit. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]

Gene Name: Ribosomal Protein L18

Chromosome: CHR19: 49118587 -49122433

Locus: 19q13.33

DDX27 Gene Summary

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein involved in the processing of 5.8S and 28S ribosomal RNAs. More specifically, the encoded protein localizes to the nucleolus, where it interacts with the PeBoW complex to ensure proper 3' end formation of 47S rRNA. [provided by RefSeq, Jan 2017]

Gene Name: DEAD-box Helicase 27

Chromosome: CHR20: 47835831 -47860614

Locus: 20q13.13

Gene Diseases

The RPL18 DDX27 Fusion has been associated with the following diseases:

Disease Name
Uterine Carcinosarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.