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RPL8-FMN1 Fusion FISH Probe

The RPL8-FMN1 Fusion FISH Probe is used to confirm a fusion of the RPL8 and FMN1 genes. The fusion of the RPL8 and FMN1 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
RPL8-FMN1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
RPL8-FMN1-20-RERE 20 (40 μL) 200 μL
RPL8-FMN1-20-REOR 20 (40 μL) 200 μL
RPL8-FMN1-20-REGO 20 (40 μL) 200 μL
RPL8-FMN1-20-REGR 20 (40 μL) 200 μL
RPL8-FMN1-20-REAQ 20 (40 μL) 200 μL
RPL8-FMN1-20-ORRE 20 (40 μL) 200 μL
RPL8-FMN1-20-OROR 20 (40 μL) 200 μL
RPL8-FMN1-20-ORGO 20 (40 μL) 200 μL
RPL8-FMN1-20-ORAQ 20 (40 μL) 200 μL
RPL8-FMN1-20-GORE 20 (40 μL) 200 μL
RPL8-FMN1-20-GOOR 20 (40 μL) 200 μL
RPL8-FMN1-20-GOGO 20 (40 μL) 200 μL
RPL8-FMN1-20-GOGR 20 (40 μL) 200 μL
RPL8-FMN1-20-GOAQ 20 (40 μL) 200 μL
RPL8-FMN1-20-GRRE 20 (40 μL) 200 μL
RPL8-FMN1-20-GROR 20 (40 μL) 200 μL
RPL8-FMN1-20-GRGO 20 (40 μL) 200 μL
RPL8-FMN1-20-GRGR 20 (40 μL) 200 μL
RPL8-FMN1-20-GRAQ 20 (40 μL) 200 μL
RPL8-FMN1-20-AQRE 20 (40 μL) 200 μL
RPL8-FMN1-20-AQOR 20 (40 μL) 200 μL
RPL8-FMN1-20-AQGO 20 (40 μL) 200 μL
RPL8-FMN1-20-AQGR 20 (40 μL) 200 μL
RPL8-FMN1-20-AQAQ 20 (40 μL) 200 μL

RPL8 Gene Summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L2P family of ribosomal proteins. It is located in the cytoplasm. In rat, the protein associates with the 5.8S rRNA, very likely participates in the binding of aminoacyl-tRNA, and is a constituent of the elongation factor 2-binding site at the ribosomal subunit interface. Alternatively spliced transcript variants encoding the same protein exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Gene Name: Ribosomal Protein L8

Chromosome: CHR8: 146015153 -146017805

Locus: 8q24.3

FMN1 Gene Summary

This gene belongs to the formin homology family and encodes a protein that has a role in the formation of adherens junction and the polymerization of linear actin cables. The homologous gene in mouse is associated with limb deformity. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]

Gene Name: Formin 1

Chromosome: CHR15: 33057746 -33360085

Locus: 15q13.3

Gene Diseases

The RPL8 FMN1 Fusion has been associated with the following diseases:

Disease Name
Skin Cutaneous Melanoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.