RSU1-LARP4B Fusion FISH Probe
The RSU1-LARP4B Fusion FISH Probe is used to confirm a fusion of the RSU1 and LARP4B genes. The fusion of the RSU1 and LARP4B genes has been associated with Cholangiocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RSU1-LARP4B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RSU1-LARP4B-20-RERE | 20 (40 μL) | 200 μL |
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| RSU1-LARP4B-20-REOR | 20 (40 μL) | 200 μL |
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| RSU1-LARP4B-20-REGO | 20 (40 μL) | 200 μL |
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| RSU1-LARP4B-20-REGR | 20 (40 μL) | 200 μL |
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| RSU1-LARP4B-20-REAQ | 20 (40 μL) | 200 μL |
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| RSU1-LARP4B-20-ORRE | 20 (40 μL) | 200 μL |
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| RSU1-LARP4B-20-OROR | 20 (40 μL) | 200 μL |
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| RSU1-LARP4B-20-ORGO | 20 (40 μL) | 200 μL |
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| RSU1-LARP4B-20-ORAQ | 20 (40 μL) | 200 μL |
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| RSU1-LARP4B-20-GORE | 20 (40 μL) | 200 μL |
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| RSU1-LARP4B-20-GOOR | 20 (40 μL) | 200 μL |
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| RSU1-LARP4B-20-GOGO | 20 (40 μL) | 200 μL |
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| RSU1-LARP4B-20-GOGR | 20 (40 μL) | 200 μL |
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| RSU1-LARP4B-20-GOAQ | 20 (40 μL) | 200 μL |
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| RSU1-LARP4B-20-GRRE | 20 (40 μL) | 200 μL |
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| RSU1-LARP4B-20-GROR | 20 (40 μL) | 200 μL |
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| RSU1-LARP4B-20-GRGO | 20 (40 μL) | 200 μL |
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| RSU1-LARP4B-20-GRGR | 20 (40 μL) | 200 μL |
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| RSU1-LARP4B-20-GRAQ | 20 (40 μL) | 200 μL |
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| RSU1-LARP4B-20-AQRE | 20 (40 μL) | 200 μL |
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| RSU1-LARP4B-20-AQOR | 20 (40 μL) | 200 μL |
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| RSU1-LARP4B-20-AQGO | 20 (40 μL) | 200 μL |
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| RSU1-LARP4B-20-AQGR | 20 (40 μL) | 200 μL |
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| RSU1-LARP4B-20-AQAQ | 20 (40 μL) | 200 μL |
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RSU1 Gene Summary
This gene encodes a protein that is involved in the Ras signal transduction pathway, growth inhibition, and nerve-growth factor induced differentiation processes, as determined in mouse and human cell line studies. In mouse, the encoded protein was initially isolated based on its ability to inhibit v-Ras transformation. Multiple alternatively spliced transcript variants for this gene have been reported; one of these variants was found only in glioma tumors. [provided by RefSeq, Jul 2008]
Gene Name: Ras Suppressor Protein 1
Chromosome: CHR10: 16632616 -16859453
Locus: 10p13
LARP4B Gene Summary
This gene encodes a member of an evolutionarily conserved protein family implicated in RNA metabolism and translation. Members of this family are characterized by the presence of an La motif, which is often located adjacent to one or more RNA recognition motifs (RRM). Together, the two motifs constitute the functional region of the protein and enable its interaction with the RNA substrate. This protein family is divided into five sub-families: the genuine La proteins and four La-related protein (LARP) sub-families. The protein encoded by this gene belongs to LARP sub-family 4. It is a cytoplasmic protein that may play a stimulatory role in translation. [provided by RefSeq, Oct 2012]
Gene Name: La Ribonucleoprotein Domain Family Member 4B
Chromosome: CHR10: 855483 -931702
Locus: 10p15.3
Gene Diseases
The RSU1 LARP4B Fusion has been associated with the following diseases:
| Disease Name |
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| Cholangiocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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