RTKN-C2ORF65 Fusion FISH Probe
The RTKN-C2ORF65 Fusion FISH Probe is used to confirm a fusion of the RTKN and C2ORF65 genes. The fusion of the RTKN and C2ORF65 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RTKN-C2ORF65-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RTKN-C2ORF65-20-RERE | 20 (40 μL) | 200 μL |
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| RTKN-C2ORF65-20-REOR | 20 (40 μL) | 200 μL |
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| RTKN-C2ORF65-20-REGO | 20 (40 μL) | 200 μL |
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| RTKN-C2ORF65-20-REGR | 20 (40 μL) | 200 μL |
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| RTKN-C2ORF65-20-REAQ | 20 (40 μL) | 200 μL |
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| RTKN-C2ORF65-20-ORRE | 20 (40 μL) | 200 μL |
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| RTKN-C2ORF65-20-OROR | 20 (40 μL) | 200 μL |
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| RTKN-C2ORF65-20-ORGO | 20 (40 μL) | 200 μL |
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| RTKN-C2ORF65-20-ORAQ | 20 (40 μL) | 200 μL |
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| RTKN-C2ORF65-20-GORE | 20 (40 μL) | 200 μL |
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| RTKN-C2ORF65-20-GOOR | 20 (40 μL) | 200 μL |
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| RTKN-C2ORF65-20-GOGO | 20 (40 μL) | 200 μL |
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| RTKN-C2ORF65-20-GOGR | 20 (40 μL) | 200 μL |
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| RTKN-C2ORF65-20-GOAQ | 20 (40 μL) | 200 μL |
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| RTKN-C2ORF65-20-GRRE | 20 (40 μL) | 200 μL |
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| RTKN-C2ORF65-20-GROR | 20 (40 μL) | 200 μL |
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| RTKN-C2ORF65-20-GRGO | 20 (40 μL) | 200 μL |
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| RTKN-C2ORF65-20-GRGR | 20 (40 μL) | 200 μL |
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| RTKN-C2ORF65-20-GRAQ | 20 (40 μL) | 200 μL |
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| RTKN-C2ORF65-20-AQRE | 20 (40 μL) | 200 μL |
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| RTKN-C2ORF65-20-AQOR | 20 (40 μL) | 200 μL |
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| RTKN-C2ORF65-20-AQGO | 20 (40 μL) | 200 μL |
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| RTKN-C2ORF65-20-AQGR | 20 (40 μL) | 200 μL |
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| RTKN-C2ORF65-20-AQAQ | 20 (40 μL) | 200 μL |
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RTKN Gene Summary
This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Rhotekin
Chromosome: CHR2: 74652987 -74669060
Locus: 2p13.1
Gene Diseases
The RTKN C2ORF65 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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