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RUNX1-DTD1 Fusion FISH Probe

The RUNX1-DTD1 Fusion FISH Probe is used to confirm a fusion of the RUNX1 and DTD1 genes. The fusion of the RUNX1 and DTD1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
RUNX1-DTD1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
RUNX1-DTD1-20-RERE 20 (40 μL) 200 μL
RUNX1-DTD1-20-REOR 20 (40 μL) 200 μL
RUNX1-DTD1-20-REGO 20 (40 μL) 200 μL
RUNX1-DTD1-20-REGR 20 (40 μL) 200 μL
RUNX1-DTD1-20-REAQ 20 (40 μL) 200 μL
RUNX1-DTD1-20-ORRE 20 (40 μL) 200 μL
RUNX1-DTD1-20-OROR 20 (40 μL) 200 μL
RUNX1-DTD1-20-ORGO 20 (40 μL) 200 μL
RUNX1-DTD1-20-ORAQ 20 (40 μL) 200 μL
RUNX1-DTD1-20-GORE 20 (40 μL) 200 μL
RUNX1-DTD1-20-GOOR 20 (40 μL) 200 μL
RUNX1-DTD1-20-GOGO 20 (40 μL) 200 μL
RUNX1-DTD1-20-GOGR 20 (40 μL) 200 μL
RUNX1-DTD1-20-GOAQ 20 (40 μL) 200 μL
RUNX1-DTD1-20-GRRE 20 (40 μL) 200 μL
RUNX1-DTD1-20-GROR 20 (40 μL) 200 μL
RUNX1-DTD1-20-GRGO 20 (40 μL) 200 μL
RUNX1-DTD1-20-GRGR 20 (40 μL) 200 μL
RUNX1-DTD1-20-GRAQ 20 (40 μL) 200 μL
RUNX1-DTD1-20-AQRE 20 (40 μL) 200 μL
RUNX1-DTD1-20-AQOR 20 (40 μL) 200 μL
RUNX1-DTD1-20-AQGO 20 (40 μL) 200 μL
RUNX1-DTD1-20-AQGR 20 (40 μL) 200 μL
RUNX1-DTD1-20-AQAQ 20 (40 μL) 200 μL

RUNX1 Gene Summary

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Name: Runt Related Transcription Factor 1

Chromosome: CHR21: 36160097 -36421595

Locus: 21q22.12

DTD1 Gene Summary

The protein encoded by this gene is similar in sequence to histidyl-tRNA synthetase, which hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). The encoded protein binds the DNA unwinding element and plays a role in the initiation of DNA replication. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]

Gene Name: D-tyrosyl-tRNA Deacylase 1

Chromosome: CHR20: 18568555 -18744560

Locus: 20p11.23

Gene Diseases

The RUNX1 DTD1 Fusion has been associated with the following diseases:

Disease Name
Breast Invasive Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.