RUNX2-IFT88 Fusion FISH Probe
The RUNX2-IFT88 Fusion FISH Probe is used to confirm a fusion of the RUNX2 and IFT88 genes. The fusion of the RUNX2 and IFT88 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RUNX2-IFT88-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RUNX2-IFT88-20-RERE | 20 (40 μL) | 200 μL |
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| RUNX2-IFT88-20-REOR | 20 (40 μL) | 200 μL |
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| RUNX2-IFT88-20-REGO | 20 (40 μL) | 200 μL |
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| RUNX2-IFT88-20-REGR | 20 (40 μL) | 200 μL |
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| RUNX2-IFT88-20-REAQ | 20 (40 μL) | 200 μL |
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| RUNX2-IFT88-20-ORRE | 20 (40 μL) | 200 μL |
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| RUNX2-IFT88-20-OROR | 20 (40 μL) | 200 μL |
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| RUNX2-IFT88-20-ORGO | 20 (40 μL) | 200 μL |
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| RUNX2-IFT88-20-ORAQ | 20 (40 μL) | 200 μL |
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| RUNX2-IFT88-20-GORE | 20 (40 μL) | 200 μL |
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| RUNX2-IFT88-20-GOOR | 20 (40 μL) | 200 μL |
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| RUNX2-IFT88-20-GOGO | 20 (40 μL) | 200 μL |
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| RUNX2-IFT88-20-GOGR | 20 (40 μL) | 200 μL |
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| RUNX2-IFT88-20-GOAQ | 20 (40 μL) | 200 μL |
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| RUNX2-IFT88-20-GRRE | 20 (40 μL) | 200 μL |
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| RUNX2-IFT88-20-GROR | 20 (40 μL) | 200 μL |
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| RUNX2-IFT88-20-GRGO | 20 (40 μL) | 200 μL |
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| RUNX2-IFT88-20-GRGR | 20 (40 μL) | 200 μL |
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| RUNX2-IFT88-20-GRAQ | 20 (40 μL) | 200 μL |
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| RUNX2-IFT88-20-AQRE | 20 (40 μL) | 200 μL |
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| RUNX2-IFT88-20-AQOR | 20 (40 μL) | 200 μL |
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| RUNX2-IFT88-20-AQGO | 20 (40 μL) | 200 μL |
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| RUNX2-IFT88-20-AQGR | 20 (40 μL) | 200 μL |
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| RUNX2-IFT88-20-AQAQ | 20 (40 μL) | 200 μL |
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RUNX2 Gene Summary
This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Two regions of potential trinucleotide repeat expansions are present in the N-terminal region of the encoded protein, and these and other mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq, Jul 2016]
Gene Name: Runt Related Transcription Factor 2
Chromosome: CHR6: 45296053 -45518819
Locus: 6p21.1
IFT88 Gene Summary
This gene encodes a member of the tetratrico peptide repeat (TPR) family. The encoded protein is involved in cilium biogenesis. Mutations of a similar gene in mouse can cause polycystic kidney disease. Several transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2017]
Gene Name: Intraflagellar Transport 88
Chromosome: CHR13: 21141207 -21265576
Locus: 13q12.11
Gene Diseases
The RUNX2 IFT88 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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