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RXRA-WDR5 Fusion FISH Probe

The RXRA-WDR5 Fusion FISH Probe is used to confirm a fusion of the RXRA and WDR5 genes. The fusion of the RXRA and WDR5 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
RXRA-WDR5-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
RXRA-WDR5-20-RERE 20 (40 μL) 200 μL
RXRA-WDR5-20-REOR 20 (40 μL) 200 μL
RXRA-WDR5-20-REGO 20 (40 μL) 200 μL
RXRA-WDR5-20-REGR 20 (40 μL) 200 μL
RXRA-WDR5-20-REAQ 20 (40 μL) 200 μL
RXRA-WDR5-20-ORRE 20 (40 μL) 200 μL
RXRA-WDR5-20-OROR 20 (40 μL) 200 μL
RXRA-WDR5-20-ORGO 20 (40 μL) 200 μL
RXRA-WDR5-20-ORAQ 20 (40 μL) 200 μL
RXRA-WDR5-20-GORE 20 (40 μL) 200 μL
RXRA-WDR5-20-GOOR 20 (40 μL) 200 μL
RXRA-WDR5-20-GOGO 20 (40 μL) 200 μL
RXRA-WDR5-20-GOGR 20 (40 μL) 200 μL
RXRA-WDR5-20-GOAQ 20 (40 μL) 200 μL
RXRA-WDR5-20-GRRE 20 (40 μL) 200 μL
RXRA-WDR5-20-GROR 20 (40 μL) 200 μL
RXRA-WDR5-20-GRGO 20 (40 μL) 200 μL
RXRA-WDR5-20-GRGR 20 (40 μL) 200 μL
RXRA-WDR5-20-GRAQ 20 (40 μL) 200 μL
RXRA-WDR5-20-AQRE 20 (40 μL) 200 μL
RXRA-WDR5-20-AQOR 20 (40 μL) 200 μL
RXRA-WDR5-20-AQGO 20 (40 μL) 200 μL
RXRA-WDR5-20-AQGR 20 (40 μL) 200 μL
RXRA-WDR5-20-AQAQ 20 (40 μL) 200 μL

RXRA Gene Summary

Retinoid X receptors (RXRs) and retinoic acid receptors (RARs) are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors function as transcription factors by binding as homodimers or heterodimers to specific sequences in the promoters of target genes. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014]

Gene Name: Retinoid X Receptor Alpha

Chromosome: CHR9: 137218315 -137332431

Locus: 9q34.2

WDR5 Gene Summary

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]

Gene Name: WD Repeat Domain 5

Chromosome: CHR9: 137001209 -137025094

Locus: 9q34.2

Gene Diseases

The RXRA WDR5 Fusion has been associated with the following diseases:

Disease Name
Liver Hepatocellular Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.