RYR2-GPR137B Fusion FISH Probe
The RYR2-GPR137B Fusion FISH Probe is used to confirm a fusion of the RYR2 and GPR137B genes. The fusion of the RYR2 and GPR137B genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RYR2-GPR137B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RYR2-GPR137B-20-RERE | 20 (40 μL) | 200 μL |
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| RYR2-GPR137B-20-REOR | 20 (40 μL) | 200 μL |
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| RYR2-GPR137B-20-REGO | 20 (40 μL) | 200 μL |
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| RYR2-GPR137B-20-REGR | 20 (40 μL) | 200 μL |
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| RYR2-GPR137B-20-REAQ | 20 (40 μL) | 200 μL |
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| RYR2-GPR137B-20-ORRE | 20 (40 μL) | 200 μL |
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| RYR2-GPR137B-20-OROR | 20 (40 μL) | 200 μL |
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| RYR2-GPR137B-20-ORGO | 20 (40 μL) | 200 μL |
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| RYR2-GPR137B-20-ORAQ | 20 (40 μL) | 200 μL |
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| RYR2-GPR137B-20-GORE | 20 (40 μL) | 200 μL |
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| RYR2-GPR137B-20-GOOR | 20 (40 μL) | 200 μL |
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| RYR2-GPR137B-20-GOGO | 20 (40 μL) | 200 μL |
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| RYR2-GPR137B-20-GOGR | 20 (40 μL) | 200 μL |
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| RYR2-GPR137B-20-GOAQ | 20 (40 μL) | 200 μL |
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| RYR2-GPR137B-20-GRRE | 20 (40 μL) | 200 μL |
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| RYR2-GPR137B-20-GROR | 20 (40 μL) | 200 μL |
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| RYR2-GPR137B-20-GRGO | 20 (40 μL) | 200 μL |
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| RYR2-GPR137B-20-GRGR | 20 (40 μL) | 200 μL |
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| RYR2-GPR137B-20-GRAQ | 20 (40 μL) | 200 μL |
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| RYR2-GPR137B-20-AQRE | 20 (40 μL) | 200 μL |
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| RYR2-GPR137B-20-AQOR | 20 (40 μL) | 200 μL |
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| RYR2-GPR137B-20-AQGO | 20 (40 μL) | 200 μL |
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| RYR2-GPR137B-20-AQGR | 20 (40 μL) | 200 μL |
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| RYR2-GPR137B-20-AQAQ | 20 (40 μL) | 200 μL |
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RYR2 Gene Summary
This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia. [provided by RefSeq, Jul 2008]
Gene Name: Ryanodine Receptor 2
Chromosome: CHR1: 237205701 -237997288
Locus: 1q43
GPR137B Gene Summary
The G Protein-coupled Receptor 137B (GPR137B) gene is located on chr1 :236305831-236372209 at 1q42.3.
Gene Name: G Protein-coupled Receptor 137B
Chromosome: CHR1: 236305831 -236372209
Locus: 1q42.3
Gene Diseases
The RYR2 GPR137B Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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