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RYR2-WLS Fusion FISH Probe

The RYR2-WLS Fusion FISH Probe is used to confirm a fusion of the RYR2 and WLS genes. The fusion of the RYR2 and WLS genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
RYR2-WLS-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
RYR2-WLS-20-RERE 20 (40 μL) 200 μL
RYR2-WLS-20-REOR 20 (40 μL) 200 μL
RYR2-WLS-20-REGO 20 (40 μL) 200 μL
RYR2-WLS-20-REGR 20 (40 μL) 200 μL
RYR2-WLS-20-REAQ 20 (40 μL) 200 μL
RYR2-WLS-20-ORRE 20 (40 μL) 200 μL
RYR2-WLS-20-OROR 20 (40 μL) 200 μL
RYR2-WLS-20-ORGO 20 (40 μL) 200 μL
RYR2-WLS-20-ORAQ 20 (40 μL) 200 μL
RYR2-WLS-20-GORE 20 (40 μL) 200 μL
RYR2-WLS-20-GOOR 20 (40 μL) 200 μL
RYR2-WLS-20-GOGO 20 (40 μL) 200 μL
RYR2-WLS-20-GOGR 20 (40 μL) 200 μL
RYR2-WLS-20-GOAQ 20 (40 μL) 200 μL
RYR2-WLS-20-GRRE 20 (40 μL) 200 μL
RYR2-WLS-20-GROR 20 (40 μL) 200 μL
RYR2-WLS-20-GRGO 20 (40 μL) 200 μL
RYR2-WLS-20-GRGR 20 (40 μL) 200 μL
RYR2-WLS-20-GRAQ 20 (40 μL) 200 μL
RYR2-WLS-20-AQRE 20 (40 μL) 200 μL
RYR2-WLS-20-AQOR 20 (40 μL) 200 μL
RYR2-WLS-20-AQGO 20 (40 μL) 200 μL
RYR2-WLS-20-AQGR 20 (40 μL) 200 μL
RYR2-WLS-20-AQAQ 20 (40 μL) 200 μL

RYR2 Gene Summary

This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia. [provided by RefSeq, Jul 2008]

Gene Name: Ryanodine Receptor 2

Chromosome: CHR1: 237205701 -237997288

Locus: 1q43

WLS Gene Summary

The Wntless Wnt Ligand Secretion Mediator (WLS) gene is located on chr1 :68564141-68698229 at 1p31.3.

Gene Name: Wntless Wnt Ligand Secretion Mediator

Chromosome: CHR1: 68564141 -68698229

Locus: 1p31.3

Gene Diseases

The RYR2 WLS Fusion has been associated with the following diseases:

Disease Name
Brain Lower Grade Glioma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.