S100A4-ELK3 Fusion FISH Probe
The S100A4-ELK3 Fusion FISH Probe is used to confirm a fusion of the S100A4 and ELK3 genes. The fusion of the S100A4 and ELK3 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| S100A4-ELK3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| S100A4-ELK3-20-RERE | 20 (40 μL) | 200 μL |
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| S100A4-ELK3-20-REOR | 20 (40 μL) | 200 μL |
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| S100A4-ELK3-20-REGO | 20 (40 μL) | 200 μL |
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| S100A4-ELK3-20-REGR | 20 (40 μL) | 200 μL |
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| S100A4-ELK3-20-REAQ | 20 (40 μL) | 200 μL |
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| S100A4-ELK3-20-ORRE | 20 (40 μL) | 200 μL |
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| S100A4-ELK3-20-OROR | 20 (40 μL) | 200 μL |
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| S100A4-ELK3-20-ORGO | 20 (40 μL) | 200 μL |
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| S100A4-ELK3-20-ORAQ | 20 (40 μL) | 200 μL |
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| S100A4-ELK3-20-GORE | 20 (40 μL) | 200 μL |
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| S100A4-ELK3-20-GOOR | 20 (40 μL) | 200 μL |
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| S100A4-ELK3-20-GOGO | 20 (40 μL) | 200 μL |
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| S100A4-ELK3-20-GOGR | 20 (40 μL) | 200 μL |
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| S100A4-ELK3-20-GOAQ | 20 (40 μL) | 200 μL |
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| S100A4-ELK3-20-GRRE | 20 (40 μL) | 200 μL |
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| S100A4-ELK3-20-GROR | 20 (40 μL) | 200 μL |
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| S100A4-ELK3-20-GRGO | 20 (40 μL) | 200 μL |
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| S100A4-ELK3-20-GRGR | 20 (40 μL) | 200 μL |
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| S100A4-ELK3-20-GRAQ | 20 (40 μL) | 200 μL |
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| S100A4-ELK3-20-AQRE | 20 (40 μL) | 200 μL |
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| S100A4-ELK3-20-AQOR | 20 (40 μL) | 200 μL |
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| S100A4-ELK3-20-AQGO | 20 (40 μL) | 200 μL |
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| S100A4-ELK3-20-AQGR | 20 (40 μL) | 200 μL |
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| S100A4-ELK3-20-AQAQ | 20 (40 μL) | 200 μL |
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ELK3 Gene Summary
This gene encodes a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Gene Name: ELK3, ETS Transcription Factor
Chromosome: CHR12: 96588206 -96661606
Locus: 12q23.1
S100A4 Gene Summary
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
Gene Name: S100 Calcium Binding Protein A4
Chromosome: CHR1: 153516094 -153518282
Locus: 1q21.3
Gene Diseases
The S100A4 ELK3 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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