S100A8-FADS2 Fusion FISH Probe
The S100A8-FADS2 Fusion FISH Probe is used to confirm a fusion of the S100A8 and FADS2 genes. The fusion of the S100A8 and FADS2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| S100A8-FADS2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| S100A8-FADS2-20-RERE | 20 (40 μL) | 200 μL |
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| S100A8-FADS2-20-REOR | 20 (40 μL) | 200 μL |
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| S100A8-FADS2-20-REGO | 20 (40 μL) | 200 μL |
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| S100A8-FADS2-20-REGR | 20 (40 μL) | 200 μL |
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| S100A8-FADS2-20-REAQ | 20 (40 μL) | 200 μL |
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| S100A8-FADS2-20-ORRE | 20 (40 μL) | 200 μL |
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| S100A8-FADS2-20-OROR | 20 (40 μL) | 200 μL |
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| S100A8-FADS2-20-ORGO | 20 (40 μL) | 200 μL |
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| S100A8-FADS2-20-ORAQ | 20 (40 μL) | 200 μL |
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| S100A8-FADS2-20-GORE | 20 (40 μL) | 200 μL |
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| S100A8-FADS2-20-GOOR | 20 (40 μL) | 200 μL |
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| S100A8-FADS2-20-GOGO | 20 (40 μL) | 200 μL |
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| S100A8-FADS2-20-GOGR | 20 (40 μL) | 200 μL |
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| S100A8-FADS2-20-GOAQ | 20 (40 μL) | 200 μL |
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| S100A8-FADS2-20-GRRE | 20 (40 μL) | 200 μL |
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| S100A8-FADS2-20-GROR | 20 (40 μL) | 200 μL |
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| S100A8-FADS2-20-GRGO | 20 (40 μL) | 200 μL |
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| S100A8-FADS2-20-GRGR | 20 (40 μL) | 200 μL |
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| S100A8-FADS2-20-GRAQ | 20 (40 μL) | 200 μL |
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| S100A8-FADS2-20-AQRE | 20 (40 μL) | 200 μL |
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| S100A8-FADS2-20-AQOR | 20 (40 μL) | 200 μL |
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| S100A8-FADS2-20-AQGO | 20 (40 μL) | 200 μL |
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| S100A8-FADS2-20-AQGR | 20 (40 μL) | 200 μL |
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| S100A8-FADS2-20-AQAQ | 20 (40 μL) | 200 μL |
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S100A8 Gene Summary
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]
Gene Name: S100 Calcium Binding Protein A8
Chromosome: CHR1: 153362507 -153363664
Locus: 1q21.3
FADS2 Gene Summary
The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
Gene Name: Fatty Acid Desaturase 2
Chromosome: CHR11: 61595712 -61634825
Locus: 11q12.2
Gene Diseases
The S100A8 FADS2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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