S100A8-MYO6 Fusion FISH Probe
The S100A8-MYO6 Fusion FISH Probe is used to confirm a fusion of the S100A8 and MYO6 genes. The fusion of the S100A8 and MYO6 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| S100A8-MYO6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| S100A8-MYO6-20-RERE | 20 (40 μL) | 200 μL |
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| S100A8-MYO6-20-REOR | 20 (40 μL) | 200 μL |
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| S100A8-MYO6-20-REGO | 20 (40 μL) | 200 μL |
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| S100A8-MYO6-20-REGR | 20 (40 μL) | 200 μL |
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| S100A8-MYO6-20-REAQ | 20 (40 μL) | 200 μL |
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| S100A8-MYO6-20-ORRE | 20 (40 μL) | 200 μL |
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| S100A8-MYO6-20-OROR | 20 (40 μL) | 200 μL |
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| S100A8-MYO6-20-ORGO | 20 (40 μL) | 200 μL |
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| S100A8-MYO6-20-ORAQ | 20 (40 μL) | 200 μL |
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| S100A8-MYO6-20-GORE | 20 (40 μL) | 200 μL |
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| S100A8-MYO6-20-GOOR | 20 (40 μL) | 200 μL |
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| S100A8-MYO6-20-GOGO | 20 (40 μL) | 200 μL |
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| S100A8-MYO6-20-GOGR | 20 (40 μL) | 200 μL |
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| S100A8-MYO6-20-GOAQ | 20 (40 μL) | 200 μL |
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| S100A8-MYO6-20-GRRE | 20 (40 μL) | 200 μL |
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| S100A8-MYO6-20-GROR | 20 (40 μL) | 200 μL |
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| S100A8-MYO6-20-GRGO | 20 (40 μL) | 200 μL |
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| S100A8-MYO6-20-GRGR | 20 (40 μL) | 200 μL |
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| S100A8-MYO6-20-GRAQ | 20 (40 μL) | 200 μL |
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| S100A8-MYO6-20-AQRE | 20 (40 μL) | 200 μL |
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| S100A8-MYO6-20-AQOR | 20 (40 μL) | 200 μL |
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| S100A8-MYO6-20-AQGO | 20 (40 μL) | 200 μL |
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| S100A8-MYO6-20-AQGR | 20 (40 μL) | 200 μL |
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| S100A8-MYO6-20-AQAQ | 20 (40 μL) | 200 μL |
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MYO6 Gene Summary
This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]
Gene Name: Myosin VI
Chromosome: CHR6: 76458908 -76629254
Locus: 6q14.1
S100A8 Gene Summary
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]
Gene Name: S100 Calcium Binding Protein A8
Chromosome: CHR1: 153362507 -153363664
Locus: 1q21.3
Gene Diseases
The S100A8 MYO6 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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