S100A8-SUPT16H Fusion FISH Probe
The S100A8-SUPT16H Fusion FISH Probe is used to confirm a fusion of the S100A8 and SUPT16H genes. The fusion of the S100A8 and SUPT16H genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| S100A8-SUPT16H-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| S100A8-SUPT16H-20-RERE | 20 (40 μL) | 200 μL |
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| S100A8-SUPT16H-20-REOR | 20 (40 μL) | 200 μL |
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| S100A8-SUPT16H-20-REGO | 20 (40 μL) | 200 μL |
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| S100A8-SUPT16H-20-REGR | 20 (40 μL) | 200 μL |
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| S100A8-SUPT16H-20-REAQ | 20 (40 μL) | 200 μL |
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| S100A8-SUPT16H-20-ORRE | 20 (40 μL) | 200 μL |
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| S100A8-SUPT16H-20-OROR | 20 (40 μL) | 200 μL |
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| S100A8-SUPT16H-20-ORGO | 20 (40 μL) | 200 μL |
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| S100A8-SUPT16H-20-ORAQ | 20 (40 μL) | 200 μL |
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| S100A8-SUPT16H-20-GORE | 20 (40 μL) | 200 μL |
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| S100A8-SUPT16H-20-GOOR | 20 (40 μL) | 200 μL |
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| S100A8-SUPT16H-20-GOGO | 20 (40 μL) | 200 μL |
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| S100A8-SUPT16H-20-GOGR | 20 (40 μL) | 200 μL |
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| S100A8-SUPT16H-20-GOAQ | 20 (40 μL) | 200 μL |
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| S100A8-SUPT16H-20-GRRE | 20 (40 μL) | 200 μL |
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| S100A8-SUPT16H-20-GROR | 20 (40 μL) | 200 μL |
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| S100A8-SUPT16H-20-GRGO | 20 (40 μL) | 200 μL |
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| S100A8-SUPT16H-20-GRGR | 20 (40 μL) | 200 μL |
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| S100A8-SUPT16H-20-GRAQ | 20 (40 μL) | 200 μL |
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| S100A8-SUPT16H-20-AQRE | 20 (40 μL) | 200 μL |
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| S100A8-SUPT16H-20-AQOR | 20 (40 μL) | 200 μL |
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| S100A8-SUPT16H-20-AQGO | 20 (40 μL) | 200 μL |
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| S100A8-SUPT16H-20-AQGR | 20 (40 μL) | 200 μL |
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| S100A8-SUPT16H-20-AQAQ | 20 (40 μL) | 200 μL |
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S100A8 Gene Summary
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]
Gene Name: S100 Calcium Binding Protein A8
Chromosome: CHR1: 153362507 -153363664
Locus: 1q21.3
SUPT16H Gene Summary
Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit; this gene encodes the 140 kDa subunit. [provided by RefSeq, Feb 2009]
Gene Name: SPT16 Homolog, Facilitates Chromatin Remodeling Subunit
Chromosome: CHR14: 21819630 -21852425
Locus: 14q11.2
Gene Diseases
The S100A8 SUPT16H Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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