S100A9-PLAT Fusion FISH Probe
The S100A9-PLAT Fusion FISH Probe is used to confirm a fusion of the S100A9 and PLAT genes. The fusion of the S100A9 and PLAT genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| S100A9-PLAT-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| S100A9-PLAT-20-RERE | 20 (40 μL) | 200 μL |
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| S100A9-PLAT-20-REOR | 20 (40 μL) | 200 μL |
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| S100A9-PLAT-20-REGO | 20 (40 μL) | 200 μL |
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| S100A9-PLAT-20-REGR | 20 (40 μL) | 200 μL |
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| S100A9-PLAT-20-REAQ | 20 (40 μL) | 200 μL |
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| S100A9-PLAT-20-ORRE | 20 (40 μL) | 200 μL |
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| S100A9-PLAT-20-OROR | 20 (40 μL) | 200 μL |
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| S100A9-PLAT-20-ORGO | 20 (40 μL) | 200 μL |
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| S100A9-PLAT-20-ORAQ | 20 (40 μL) | 200 μL |
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| S100A9-PLAT-20-GORE | 20 (40 μL) | 200 μL |
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| S100A9-PLAT-20-GOOR | 20 (40 μL) | 200 μL |
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| S100A9-PLAT-20-GOGO | 20 (40 μL) | 200 μL |
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| S100A9-PLAT-20-GOGR | 20 (40 μL) | 200 μL |
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| S100A9-PLAT-20-GOAQ | 20 (40 μL) | 200 μL |
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| S100A9-PLAT-20-GRRE | 20 (40 μL) | 200 μL |
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| S100A9-PLAT-20-GROR | 20 (40 μL) | 200 μL |
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| S100A9-PLAT-20-GRGO | 20 (40 μL) | 200 μL |
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| S100A9-PLAT-20-GRGR | 20 (40 μL) | 200 μL |
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| S100A9-PLAT-20-GRAQ | 20 (40 μL) | 200 μL |
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| S100A9-PLAT-20-AQRE | 20 (40 μL) | 200 μL |
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| S100A9-PLAT-20-AQOR | 20 (40 μL) | 200 μL |
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| S100A9-PLAT-20-AQGO | 20 (40 μL) | 200 μL |
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| S100A9-PLAT-20-AQGR | 20 (40 μL) | 200 μL |
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| S100A9-PLAT-20-AQAQ | 20 (40 μL) | 200 μL |
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PLAT Gene Summary
This gene encodes tissue-type plasminogen activator, a secreted serine protease that converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. The encoded preproprotein is proteolytically processed by plasmin or trypsin to generate heavy and light chains. These chains associate via disulfide linkages to form the heterodimeric enzyme. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, while decreased activity leads to hypofibrinolysis, which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
Gene Name: Plasminogen Activator, Tissue Type
Chromosome: CHR8: 42032235 -42065194
Locus: 8p11.21
S100A9 Gene Summary
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and altered expression of this protein is associated with the disease cystic fibrosis. This antimicrobial protein exhibits antifungal and antibacterial activity. [provided by RefSeq, Nov 2014]
Gene Name: S100 Calcium Binding Protein A9
Chromosome: CHR1: 153330329 -153333503
Locus: 1q21.3
Gene Diseases
The S100A9 PLAT Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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