SACM1L-ANAPC13 Fusion FISH Probe
The SACM1L-ANAPC13 Fusion FISH Probe is used to confirm a fusion of the SACM1L and ANAPC13 genes. The fusion of the SACM1L and ANAPC13 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SACM1L-ANAPC13-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SACM1L-ANAPC13-20-RERE | 20 (40 μL) | 200 μL |
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| SACM1L-ANAPC13-20-REOR | 20 (40 μL) | 200 μL |
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| SACM1L-ANAPC13-20-REGO | 20 (40 μL) | 200 μL |
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| SACM1L-ANAPC13-20-REGR | 20 (40 μL) | 200 μL |
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| SACM1L-ANAPC13-20-REAQ | 20 (40 μL) | 200 μL |
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| SACM1L-ANAPC13-20-ORRE | 20 (40 μL) | 200 μL |
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| SACM1L-ANAPC13-20-OROR | 20 (40 μL) | 200 μL |
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| SACM1L-ANAPC13-20-ORGO | 20 (40 μL) | 200 μL |
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| SACM1L-ANAPC13-20-ORAQ | 20 (40 μL) | 200 μL |
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| SACM1L-ANAPC13-20-GORE | 20 (40 μL) | 200 μL |
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| SACM1L-ANAPC13-20-GOOR | 20 (40 μL) | 200 μL |
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| SACM1L-ANAPC13-20-GOGO | 20 (40 μL) | 200 μL |
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| SACM1L-ANAPC13-20-GOGR | 20 (40 μL) | 200 μL |
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| SACM1L-ANAPC13-20-GOAQ | 20 (40 μL) | 200 μL |
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| SACM1L-ANAPC13-20-GRRE | 20 (40 μL) | 200 μL |
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| SACM1L-ANAPC13-20-GROR | 20 (40 μL) | 200 μL |
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| SACM1L-ANAPC13-20-GRGO | 20 (40 μL) | 200 μL |
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| SACM1L-ANAPC13-20-GRGR | 20 (40 μL) | 200 μL |
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| SACM1L-ANAPC13-20-GRAQ | 20 (40 μL) | 200 μL |
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| SACM1L-ANAPC13-20-AQRE | 20 (40 μL) | 200 μL |
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| SACM1L-ANAPC13-20-AQOR | 20 (40 μL) | 200 μL |
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| SACM1L-ANAPC13-20-AQGO | 20 (40 μL) | 200 μL |
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| SACM1L-ANAPC13-20-AQGR | 20 (40 μL) | 200 μL |
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| SACM1L-ANAPC13-20-AQAQ | 20 (40 μL) | 200 μL |
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SACM1L Gene Summary
This gene encodes an integral membrane protein, which is localized to the endoplasmic reticulum, and functions as a phosphoinositide phosphatase that hydrolyzes phosphatidylinositol 3-phosphate, phosphatidylinositol 4-phosphate, and phosphatidylinositol 3,5-bisphosphate. Deletion of this gene in mouse results in preimplantation lethality. Other studies suggest that this gene is also involved in the organization of golgi membranes and mitotic spindles. Alternatively spliced transcript variants have been found for this gene. A C-terminally extended isoform is also predicted to be produced by the use of an alternative in-frame, downstream translation termination codon via a stop codon readthrough mechanism.[provided by RefSeq, Dec 2017]
Gene Name: SAC1 Like Phosphatidylinositide Phosphatase
Chromosome: CHR3: 45730753 -45786900
Locus: 3p21.31
ANAPC13 Gene Summary
This gene encodes a component of the anaphase promoting complex, a large ubiquitin-protein ligase that controls cell cycle progression by regulating the degradation of cell cycle regulators such as B-type cyclins. The encoded protein is evolutionarily conserved and is required for the integrity and ubiquitin ligase activity of the anaphase promoting complex. Pseudogenes and splice variants have been found for this gene; however, the biological validity of some of the splice variants has not been determined. [provided by RefSeq, Nov 2008]
Gene Name: Anaphase Promoting Complex Subunit 13
Chromosome: CHR3: 134196545 -134204865
Locus: 3q22.2
Gene Diseases
The SACM1L ANAPC13 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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