SAE1-FGF9 Fusion FISH Probe
The SAE1-FGF9 Fusion FISH Probe is used to confirm a fusion of the SAE1 and FGF9 genes. The fusion of the SAE1 and FGF9 genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SAE1-FGF9-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SAE1-FGF9-20-RERE | 20 (40 μL) | 200 μL |
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| SAE1-FGF9-20-REOR | 20 (40 μL) | 200 μL |
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| SAE1-FGF9-20-REGO | 20 (40 μL) | 200 μL |
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| SAE1-FGF9-20-REGR | 20 (40 μL) | 200 μL |
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| SAE1-FGF9-20-REAQ | 20 (40 μL) | 200 μL |
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| SAE1-FGF9-20-ORRE | 20 (40 μL) | 200 μL |
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| SAE1-FGF9-20-OROR | 20 (40 μL) | 200 μL |
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| SAE1-FGF9-20-ORGO | 20 (40 μL) | 200 μL |
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| SAE1-FGF9-20-ORAQ | 20 (40 μL) | 200 μL |
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| SAE1-FGF9-20-GORE | 20 (40 μL) | 200 μL |
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| SAE1-FGF9-20-GOOR | 20 (40 μL) | 200 μL |
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| SAE1-FGF9-20-GOGO | 20 (40 μL) | 200 μL |
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| SAE1-FGF9-20-GOGR | 20 (40 μL) | 200 μL |
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| SAE1-FGF9-20-GOAQ | 20 (40 μL) | 200 μL |
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| SAE1-FGF9-20-GRRE | 20 (40 μL) | 200 μL |
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| SAE1-FGF9-20-GROR | 20 (40 μL) | 200 μL |
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| SAE1-FGF9-20-GRGO | 20 (40 μL) | 200 μL |
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| SAE1-FGF9-20-GRGR | 20 (40 μL) | 200 μL |
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| SAE1-FGF9-20-GRAQ | 20 (40 μL) | 200 μL |
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| SAE1-FGF9-20-AQRE | 20 (40 μL) | 200 μL |
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| SAE1-FGF9-20-AQOR | 20 (40 μL) | 200 μL |
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| SAE1-FGF9-20-AQGO | 20 (40 μL) | 200 μL |
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| SAE1-FGF9-20-AQGR | 20 (40 μL) | 200 μL |
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| SAE1-FGF9-20-AQAQ | 20 (40 μL) | 200 μL |
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FGF9 Gene Summary
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling. Mice lacking the homolog gene displayed a male-to-female sex reversal phenotype, which suggested a role in testicular embryogenesis. [provided by RefSeq, Jul 2008]
Gene Name: Fibroblast Growth Factor 9
Chromosome: CHR13: 22245214 -22278640
Locus: 13q12.11
SAE1 Gene Summary
Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010]
Gene Name: SUMO1 Activating Enzyme Subunit 1
Chromosome: CHR19: 47634079 -47713893
Locus: 19q13.32
Gene Diseases
The SAE1 FGF9 Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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